Towards a generic physiologically based kinetic model to predict in vivo uterotrophic responses in rats by reverse dosimetry of in vitro estrogenicity data.

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Towards a generic physiologically based kinetic model to predict in vivo uterotrophic responses in rats by reverse dosimetry of in vitro estrogenicity data.

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2017 nî lūn-bûn

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2017年の論文

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Towards a generic physiologica ...... f in vitro estrogenicity data.

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Towards a generic physiologica ...... f in vitro estrogenicity data.

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Towards a generic physiologica ...... f in vitro estrogenicity data.

@en

Towards a generic physiologica ...... f in vitro estrogenicity data.

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Towards a generic physiologica ...... f in vitro estrogenicity data.

@en

Towards a generic physiologica ...... f in vitro estrogenicity data.

@nl

P1476

Towards a generic physiologica ...... f in vitro estrogenicity data.

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P2093

Eric Fabian

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Ivonne M C M Rietjens

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Jochem Louisse

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P2860

Sensitivity of the immature rat uterotrophic assay to mixtures of estrogens

The OECD program to validate the rat uterotrophic bioassay. Phase 2: dose-response studies.

Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes.

Combining in vitro embryotoxicity data with physiologically based kinetic (PBK) modelling to define in vivo dose-response curves for developmental toxicity of phenol in rat and human.

Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling.

Comparison of the use of liver models for predicting drug clearance using in vitro kinetic data from hepatic microsomes and isolated hepatocytes.

Predicting points of departure for risk assessment based on in vitro cytotoxicity data and physiologically based kinetic (PBK) modeling: The case of kidney toxicity induced by aristolochic acid I.

Use of Physiologically Based Kinetic Modeling-Based Reverse Dosimetry to Predict in Vivo Toxicity from in Vitro Data.

Integrating in vitro data and physiologically based kinetic (PBK) modelling to assess the in vivo potential developmental toxicity of a series of phenols.

Use of physiologically based kinetic modeling-facilitated reverse dosimetry of in vitro toxicity data for prediction of in vivo developmental toxicity of tebuconazole in rats.

P2888

s00204-017-2140-5

P304

1075-1088

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scholarly article

P356

10.1007/S00204-017-2140-5

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P433

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P478

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P50

Mengying Zhang

Bennard van Ravenzwaay

P577

2017-12-12T00:00:00Z

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P698

29234833

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5866837

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