about
Increased NBCn1 expression, Na+/HCO3- co-transport and intracellular pH in human vascular smooth muscle cells with a risk allele for hypertension.Cation-coupled bicarbonate transportersSplice cassette II of Na+,HCO3(-) cotransporter NBCn1 (slc4a7) interacts with calcineurin A: implications for transporter activity and intracellular pH control during rat artery contractions.Disturbed acid-base transport: an emerging cause of hypertension.Intracellular acidification alters myogenic responsiveness and vasomotion of mouse middle cerebral arteriesRegulation and roles of bicarbonate transporters in cancer.Acid-base transporters modulate cell migration, growth and proliferation: Implications for structure development and remodeling of resistance arteries?Negative News: Cl- and HCO3- in the Vascular Wall.Gram-scale solution-phase synthesis of selective sodium bicarbonate co-transport inhibitor S0859: in vitro efficacy studies in breast cancer cells.NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance.Prior renovascular hypertension does not predispose to atherosclerosis in mice.Insulin inhibits Na+/H+ exchange in vascular smooth muscle and endothelial cells in situ: involvement of H2O2 and tyrosine phosphatase SHP-2.Acid-base regulation and sensing: Accelerators and brakes in metabolic regulation of cerebrovascular tone.Extracellular acidosis and very low [Na+ ] inhibit NBCn1- and NHE1-mediated net acid extrusion from mouse vascular smooth muscle cells.The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms.Antibody-independent localization of the electroneutral Na+-HCO3- cotransporter NBCn1 (slc4a7) in mice.Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice.Na+,HCO3- -cotransport is functionally upregulated during human breast carcinogenesis and required for the inverted pH gradient across the plasma membrane.Contribution of Na+,HCO3(-)-cotransport to cellular pH control in human breast cancer: a role for the breast cancer susceptibility locus NBCn1 (SLC4A7).NHE1 knockout reduces blood pressure and arterial media/lumen ratio with no effect on resting pH(i) in the vascular wall.Perivascular tissue inhibits rho-kinase-dependent smooth muscle Ca(2+) sensitivity and endothelium-dependent H2 S signalling in rat coronary arteries.Murine breast cancer feed arteries are thin-walled with reduced α1A-adrenoceptor expression and attenuated sympathetic vasocontraction.Synthesis of N-cyano-substituted sulfilimine and sulfoximine derivatives of S0859 and their biological evaluation as sodium bicarbonate co-transport inhibitorsNa+,HCO3–-cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in miceAcidosis inhibits rhythmic contractions of human thoracic ductsUpregulated Na/H-Exchange Protects Human Colon Cancer Tissue against Intracellular AcidificationOpening of small and intermediate calcium-activated potassium channels induces relaxation mainly mediated by nitric-oxide release in large arteries and endothelium-derived hyperpolarizing factor in small arteries from ratEndothelial alkalinisation inhibits gap junction communication and endothelium-derived hyperpolarisations in mouse mesenteric arteriesNew roles of factors from perivascular tissue in regulation of vascular toneCarbonic anhydrase inhibitors modify intracellular pH transients and contractions of rat middle cerebral arteries during CO2/HCO3- fluctuationsCrosstalk between cardiomyocyte-rich perivascular tissue and coronary arteries is reduced in the Zucker Diabetic Fatty rat model of type 2 diabetes mellitusNa+, HCO3--cotransporter NBCn1 increases pHi gradients, filopodia, and migration of smooth muscle cells and promotes arterial remodellingA novel method to isolate retinal and brain microvessels from individual rats: Microscopic and molecular biological characterization and application in hyperglycemic animalsTargeting the Acidic Tumor Microenvironment: Unexpected Pro-Neoplastic Effects of Oral NaHCO3 Therapy in Murine Breast TissueEnhanced nitric oxide signaling amplifies vasorelaxation of human colon cancer feed arteries
P50
Q33614645-AEA12C2A-DF9E-45F3-AFC6-A0BCF22F8983Q36623416-4027F2CB-D859-49CC-9F80-CFFE6683856AQ36708510-2D8DDF72-2D5F-409C-9223-015292DF2880Q37409959-083A888D-59CB-4614-A6B4-D9031FD5B417Q37459924-2521D056-D81B-468E-9147-2CC1F5C0E30DQ37719006-A33B9EE2-E08D-4CB6-A40F-C2B8371BF43DQ38069713-61FB9BF8-2417-4374-A3A8-0B629947A5ABQ38924296-F547197D-BEF2-4AAE-9800-84EF69E6CD40Q39289844-E8E29C62-E749-4ABE-9088-BE6740EC48C6Q39694096-922E9FA0-0B14-4A54-9B74-453810BEC4A7Q40788308-D97B098C-D8FF-4A68-BFAF-FD0EA3432468Q46226402-3D4E07DD-2B07-44A2-8C6B-8B488A5C079FQ47752027-4EB81EA3-BD40-4CD5-886E-8DCAE6176B7EQ47945123-702BA26E-9243-467B-9F1B-4266AFD86F88Q48178908-CABADD0F-3B30-484B-9F17-278529A2F9FCQ52584001-56518264-98F5-418D-8595-9A1CE765DA43Q52616732-55A60E77-D906-4709-9AC5-27D2F0146FF2Q53238370-C16DCA13-5683-45B4-82BE-85458947BDFEQ54489613-A2A72AD3-F765-486F-9091-56BE493038ABQ54528369-010116A6-D570-44E1-A501-EA6E553EDC9DQ55043487-4AFCFDF2-61EA-440A-95A5-B407451881C6Q55393384-3987A746-0A02-471E-8E24-B31033C8090BQ57404749-DFA57675-5AD3-44E4-BC8D-241A766D6F94Q61052315-6FF1385B-08C4-4A61-A4B2-C0552A83AFDCQ64090076-57FE8902-B858-4AD6-BE4F-64711C9EC43AQ64242202-5610A42C-FB8D-4926-94CC-A443C450BBD9Q84863699-D879A182-11E1-4110-9FE3-A8D67216891BQ85850205-7BA8D7B5-A69A-4448-90EF-D0315175957FQ86545800-4402F8BB-4F64-4C10-8697-295D0F4412DBQ87609829-3365F484-6280-4594-B422-E0769820CB93Q89115488-ED3CF1C8-0731-4B33-A5F3-7B4ABF0ADEDEQ89179634-BAD778F1-3658-443C-9BA3-85DB5DC0E9A4Q90024419-0B21BFD4-01C6-4FE5-8724-9E794FAF08C4Q91734246-D00F5A1F-033D-4080-B3AB-7035994C5940Q93172271-8DA21CA6-A52C-4791-8DCD-30E960CF5E64
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Ebbe Boedtkjer
@ast
Ebbe Boedtkjer
@en
Ebbe Boedtkjer
@es
Ebbe Boedtkjer
@nl
Ebbe Boedtkjer
@sl
type
label
Ebbe Boedtkjer
@ast
Ebbe Boedtkjer
@en
Ebbe Boedtkjer
@es
Ebbe Boedtkjer
@nl
Ebbe Boedtkjer
@sl
prefLabel
Ebbe Boedtkjer
@ast
Ebbe Boedtkjer
@en
Ebbe Boedtkjer
@es
Ebbe Boedtkjer
@nl
Ebbe Boedtkjer
@sl
P1053
B-7315-2008
P106
P1153
12794048600
P21
P2798
P31
P3829
P496
0000-0002-5078-9279
P569
2000-01-01T00:00:00Z