Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE.

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Identification of new potential HIV-1 reverse transcriptase inhibitors by QSAR modeling and structure-based virtual screening.

P2860

Q47279853-9326D58A-D978-4A38-AF5C-1FD14A4B70A2

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Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE.

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http://www.wikidata.org/entity/Q47768910

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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name

Ensemble-based ADME-Tox profil ...... cysteine protease CPB2.8ΔCTE.

@en

Ensemble-based ADME-Tox profil ...... cysteine protease CPB2.8ΔCTE.

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type

Item

label

Ensemble-based ADME-Tox profil ...... cysteine protease CPB2.8ΔCTE.

@en

Ensemble-based ADME-Tox profil ...... cysteine protease CPB2.8ΔCTE.

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prefLabel

Ensemble-based ADME-Tox profil ...... cysteine protease CPB2.8ΔCTE.

@en

Ensemble-based ADME-Tox profil ...... cysteine protease CPB2.8ΔCTE.

@nl

P1476

Ensemble-based ADME-Tox profil ...... cysteine protease CPB2.8ΔCTE.

@en

P2093

Anna Piperno

http://www.w3.org/2001/XMLSchema#string

Giovanni Grassi

http://www.w3.org/2001/XMLSchema#string

Louis Maes

http://www.w3.org/2001/XMLSchema#string

Nicola Micale

http://www.w3.org/2001/XMLSchema#string

Tanja Schirmeister

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P2860

Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Irreversible inhibitors of serine, cysteine, and threonine proteases

Identification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPB

Is there a difference between leads and drugs? A historical perspective.

Cysteine protease inhibitors as chemotherapy for parasitic infections.

Repurposing human PDE4 inhibitors for neglected tropical diseases: design, synthesis and evaluation of cilomilast analogues as Trypanosoma brucei PDEB1 inhibitors

Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives.

The resurgence of covalent drugs.

Development of a New Antileishmanial Aziridine-2,3-Dicarboxylate-Based Inhibitor with High Selectivity for Parasite Cysteine Proteases.

P304

597-604

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scholarly article

P356

10.1111/CBDD.13124

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Antonio Rescifina

Angela Scala

P577

2017-10-17T00:00:00Z

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P698

29045053

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Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE.

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P2860

P2860

Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE.

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P1433

P1476

P2093

P2860

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P50

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P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698