p53 Nongenotoxic Activation and mTORC1 Inhibition Lead to Effective Combination for Neuroblastoma Therapy.

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Combined use of CDK4/6 and mTOR inhibitors induce synergistic growth arrest of diffuse intrinsic pontine glioma cells via mutual downregulation of mTORC1 activity

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Q58746764-73805CDD-66EB-4792-8BB0-B6C90B7E4B42

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p53 Nongenotoxic Activation and mTORC1 Inhibition Lead to Effective Combination for Neuroblastoma Therapy.

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http://www.wikidata.org/entity/Q48689521

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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name

p53 Nongenotoxic Activation an ...... ion for Neuroblastoma Therapy.

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p53 Nongenotoxic Activation an ...... ion for Neuroblastoma Therapy.

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type

Item

label

p53 Nongenotoxic Activation an ...... ion for Neuroblastoma Therapy.

@en

p53 Nongenotoxic Activation an ...... ion for Neuroblastoma Therapy.

@nl

prefLabel

p53 Nongenotoxic Activation an ...... ion for Neuroblastoma Therapy.

@en

p53 Nongenotoxic Activation an ...... ion for Neuroblastoma Therapy.

@nl

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p53 Nongenotoxic Activation an ...... ion for Neuroblastoma Therapy.

@en

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Anna Lakoma

http://www.w3.org/2001/XMLSchema#string

Eveline Barbieri

http://www.w3.org/2001/XMLSchema#string

Jan J Molenaar

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Jason M Shohet

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Kathleen A Scorsone

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Kevin Aviles-Padilla

http://www.w3.org/2001/XMLSchema#string

Linda Schild

http://www.w3.org/2001/XMLSchema#string

Ling Tao

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Myrthala Moreno-Smith

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Rana Nikzad

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Survivin: a unique target for tumor therapy

Discovery of RG7388, a potent and selective p53-MDM2 inhibitor in clinical development

Sestrins inhibit mTORC1 kinase activation through the GATOR complex

p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling

Validating survivin as a cancer therapeutic target

Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics

A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma

c-myc Repression of TSC2 contributes to control of translation initiation and Myc-induced transformation

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

Ras, PI(3)K and mTOR signalling controls tumour cell growth

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6629-6639

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scholarly article

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10.1158/1078-0432.CCR-17-0668

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English

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http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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S Paust

Eugene S Kim

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2017-08-18T00:00:00Z

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28821555

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5959272

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p53 Nongenotoxic Activation and mTORC1 Inhibition Lead to Effective Combination for Neuroblastoma Therapy.

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P2860

P2860

p53 Nongenotoxic Activation and mTORC1 Inhibition Lead to Effective Combination for Neuroblastoma Therapy.

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type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932