Tracking the progression of the human inner cell mass during embryonic stem cell derivation. - sprookjes - yvandenbroek - TriplyDB

Tracking the progression of the human inner cell mass during embryonic stem cell derivation.

Tracking the progression of the human inner cell mass during embryonic stem cell derivation.

http://www.wikidata.org/entity/Q48799241

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Metaboloepigenetic Regulation of Pluripotent Stem Cells Ex uno plures: molecular designs for embryonic pluripotency Signaling pathways in induced naïve pluripotency CellTree: an R/bioconductor package to infer the hierarchical structure of cell populations from single-cell RNA-seq data.Describing the Stem Cell Potency: The Various Methods of Functional Assessment and In silico Diagnostics Molecular basis of embryonic stem cell self-renewal: from signaling pathways to pluripotency network Self-organization of the human embryo in the absence of maternal tissues.The many faces of Pluripotency: in vitro adaptations of a continuum of in vivo states.Coupling of X-chromosome reactivation with the pluripotent stem cell state.Genetic and epigenetic instability in human pluripotent stem cells.Pluripotency and its layers of complexity.Defining the genomic signature of totipotency and pluripotency during early human development.Inhibition of transforming growth factor β signaling promotes epiblast formation in mouse embryos Application Of Small Molecules Favoring Naïve Pluripotency during Human Embryonic Stem Cell Derivation.Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification.Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor.Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation.Metabolic plasticity complements the unique nature and demands of distinct pluripotency states.Totipotency: what it is and what it is not Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche.Use of pluripotent stem cells for reproductive medicine: are we there yet?Totipotency and lineage segregation in the human embryo.Transcriptome analyses of inner cell mass and trophectoderm cells isolated by magnetic-activated cell sorting from bovine blastocysts using single cell RNA-seq.The post-inner cell mass intermediate: implications for stem cell biology and assisted reproductive technology.X chromosome inactivation in human pluripotent stem cells as a model for human development: back to the drawing board?Capturing the ephemeral human pluripotent state.Single-cell RNA sequencing: revealing human pre-implantation development, pluripotency and germline development.Female human pluripotent stem cells rapidly lose X chromosome inactivation marks and progress to a skewed methylation pattern during culture.Comprehensive chromosome screening and gene expression analysis from the same biopsy in human preimplantation embryos.Exogenous supplementation of Activin A enhances germ cell differentiation of human embryonic stem cells.Single-cell gene expression profiles define self-renewing, pluripotent, and lineage primed states of human pluripotent stem cells.BMP4 promotes EMT and mesodermal commitment in human embryonic stem cells via SLUG and MSX2.Dental Pulp Stem Cells Model Early Life and Imprinted DNA Methylation Patterns.Formative pluripotency: the executive phase in a developmental continuum A pluripotent stem cell-based model for post-implantation human amniotic sac development.Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1 Lineage- and developmental stage-specific mechanomodulation of induced pluripotent stem cell differentiation.The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4- and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation.

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Tracking the progression of the human inner cell mass during embryonic stem cell derivation.

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Nature Biotechnology

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Tracking the progression of th ...... mbryonic stem cell derivation.

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Björn Heindryckx

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David van Bruggen

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Mado Vandewoestyne

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Petra De Sutter

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Susana M Chuva de Sousa Lopes

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Sylvie Lierman

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Thomas O'Leary

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P2860

Metastable pluripotent states in NOD-mouse-derived ESCs

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst

Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo

BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo

Derivation of pluripotent epiblast stem cells from mammalian embryos

New cell lines from mouse epiblast share defining features with human embryonic stem cells

Nanog safeguards pluripotency and mediates germline development

Naive and primed pluripotent states

International community consensus standard for reporting derivation of human embryonic stem cell lines.

X chromosome activity in mouse XX primordial germ cells.

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10.1038/NBT.2135

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