Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex.

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Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex.

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Oral administration of a speci ...... ease in rat prefrontal cortex.

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Oral administration of a specific kynurenic acid synthesis

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Oral administration of a speci ...... ease in rat prefrontal cortex.

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Oral administration of a specific kynurenic acid synthesis

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Oral administration of a speci ...... ease in rat prefrontal cortex.

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Oral administration of a specific kynurenic acid synthesis

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P1476

Oral administration of a speci ...... ease in rat prefrontal cortex.

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P2093

D M Bortz

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H-Q Wu

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J P Bruno

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R Schwarcz

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P2860

Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II

Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior.

Kynurenines in the mammalian brain: when physiology meets pathology

PF-04859989 as a template for structure-based drug design: identification of new pyrazole series of irreversible KAT II inhibitors with improved lipophilic efficiency

Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions

The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications

Mitochondrial aspartate aminotransferase: a third kynurenate-producing enzyme in the mammalian brain

Projections from the nucleus accumbens to cholinergic neurons of the ventral pallidum: a correlated light and electron microscopic double-immunolabeling study in rat.

Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memory

Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood.

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69-78

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scholarly article

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10.1016/J.NEUROPHARM.2017.04.023

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121

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2017-04-15T00:00:00Z

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28419874

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5803791

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