The tetracycline efflux protein encoded by the tet(K) gene from Staphylococcus aureus is a metal-tetracycline/H+ antiporter.
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Twelve-transmembrane-segment (TMS) version (DeltaTMS VII-VIII) of the 14-TMS Tet(L) antibiotic resistance protein retains monovalent cation transport modes but lacks tetracycline efflux capacitySite-directed mutagenesis studies of selected motif and charged residues and of cysteines of the multifunctional tetracycline efflux protein Tet(L).Tet(L) and tet(K) tetracycline-divalent metal/H+ antiporters: characterization of multiple catalytic modes and a mutagenesis approach to differences in their efflux substrate and coupling ion preferences.Alkaline pH homeostasis in bacteria: new insights.Na+/H+ antiport activity conferred by Bacillus subtilis tetA(L), a 5' truncation product of tetA(L), and related plasmid genes upon Escherichia coli.Chromosomal tetA(L) gene of Bacillus subtilis: regulation of expression and physiology of a tetA(L) deletion strain.Glutamate residues located within putative transmembrane helices are essential for TetA(P)-mediated tetracycline efflux.Do physiological roles foster persistence of drug/multidrug-efflux transporters? A case study.Proton-dependent multidrug efflux systems.Active export proteins mediating drug resistance in staphylococci.The TetA(K) tetracycline/H(+) antiporter from Staphylococcus aureus: mutagenesis and functional analysis of motif C.Membrane topology of the metal-tetracycline/H+ antiporter TetA(K) from Staphylococcus aureus.Effects of efflux transporter genes on susceptibility of Escherichia coli to tigecycline (GAR-936).Transmembrane glutamic acid residues play essential roles in the metal-tetracycline/H+ antiporter of Staphylococcus aureus.
P2860
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P2860
The tetracycline efflux protein encoded by the tet(K) gene from Staphylococcus aureus is a metal-tetracycline/H+ antiporter.
description
1995 nî lūn-bûn
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1995年の論文
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1995年学术文章
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1995年学术文章
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1995年学术文章
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1995年学术文章
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1995年学术文章
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1995年學術文章
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name
The tetracycline efflux protein encoded by the tet
@nl
The tetracycline efflux protei ...... al-tetracycline/H+ antiporter.
@en
type
label
The tetracycline efflux protein encoded by the tet
@nl
The tetracycline efflux protei ...... al-tetracycline/H+ antiporter.
@en
prefLabel
The tetracycline efflux protein encoded by the tet
@nl
The tetracycline efflux protei ...... al-tetracycline/H+ antiporter.
@en
P2093
P2860
P1433
P1476
The tetracycline efflux protei ...... al-tetracycline/H+ antiporter.
@en
P2093
P2860
P304
P356
10.1016/0014-5793(95)00455-I
P407
P577
1995-05-01T00:00:00Z