about
FGFR1 ser-463 ser-583 ser-585 ser-653 ser-654 ser-730 ser-766 ser-776 phosphorylatedL-proline 252 replaced with L-serineL-proline 252 replaced with L-threonineL-proline 252 replaced with L-arginineL-proline 252 replaced with L-serine ser-463 ser-583 ser-585 ser-653 ser-654 ser-730 ser-766 ser-776 phosphorylatedL-proline 252 replaced with L-threonine ser-463 ser-583 ser-585 ser-653 ser-654 ser-730 ser-766 ser-776 phosphorylatedL-proline 252 replaced with L-arginine ser-463 ser-583 ser-585 ser-653 ser-654 ser-730 ser-766 ser-776 phosphorylatedL-lysine 656 replaced with L-glutamic acidL-asparagine 546 replaced with L-lysineFGFR1 ser-463 ser-583 ser-585 ser-653 ser-654 ser-730 phosphorylatedFGFR1 ser-463 ser-583 ser-585 ser-653 ser-654 ser-730 ser-766 ser-776 phosphorylated [plasma membrane]L-lysine 656 replaced with L-glutamic acid [plasma membrane]L-asparagine 546 replaced with L-lysine [plasma membrane]
P279
FGFR1c homodimerL1:FGFR1FGFR1b homodimerActivated overexpressed FGFR1b homodimerActivated overexpressed FGFR1c homodimerFGFR1c P252X mutantsFGFR1c P252S mutant dimerFGFR1c S252T mutant dimerFGFR1c P252R mutant dimerp-8Y-FGFR1c P252S dimerp-8Y-FGFR1c P252T dimerp-8Y-FGFR1c P252R dimerFGFR1 mutants with enhanced kinase activityFGFR1 K656E mutant dimerFGFR1 N546K mutant dimerp-8Y-FGFR1 K656E dimerp-8Y-FGFR1 N546K dimerplasma membrane FGFR1 fusionsFGFR1(22-763):TACC1(571-805) fusion dimerp-6Y FGFR1(22-763):TACC1(571-805) fusion dimerp-8Y-FGFR1b dimerFGFR1c:KAL1L1-FGFR cis-heterodimerizationLigand-independent dimerization of overexpressed FGFR1bLigand-independent dimerization of overexpressed FGFR1cFGFR1b binds to FGFFGFR1c binds to FGFFGFR1c binds to Klotho-bound FGF23KAL1 binds FGFR1c
P527
P688
Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificityAsymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cellsCellular signaling by fibroblast growth factor receptorsThe structure and function of vertebrate fibroblast growth factor receptor 1Complete sequence of a human receptor for acidic and basic fibroblast growth factorsDiverse forms of a receptor for acidic and basic fibroblast growth factorsThe human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domainIdentification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transductionFibroblast growth factor receptors from liver vary in three structural domainsUbiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosisA common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndromeReceptor specificity of the fibroblast growth factor familyNovel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1MicroRNA-16 and microRNA-424 regulate cell-autonomous angiogenic functions in endothelial cells via targeting vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signalAn endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertensionMiR-573 inhibits prostate cancer metastasis by regulating epithelial-mesenchymal transitionMicroRNA-198 inhibits proliferation and induces apoptosis of lung cancer cells via targeting FGFR1.
P921
Q50369612-E1C9336D-5C27-4ACD-9FCC-3E7079D628C6Q50369615-1F76BC4F-5149-4AD2-B487-C9DAD952292AQ50369617-49C02560-B476-4431-BD46-B22D1A48E9ABQ50369618-B3443349-FD1C-434B-AE81-DFB6A902271FQ50369620-E712ECFF-89DE-4D4F-BA11-4DEF153B36B3Q50369621-6B38BAE0-E3FB-4703-85F3-05B076BDD560Q50369622-B39007D4-3DDA-4CF7-922A-01DA81071FFAQ50369623-FCF30438-DEC4-45D7-9200-109CEFC00742Q50369624-6740667B-971E-47A5-BD62-B024472ECA64Q50369641-5A40392F-DEBB-43BA-A8E1-989CB37F86BFQ50677175-60A9BBCC-9436-49C4-B816-6047D2FF91BAQ50677176-8CE9C458-89B0-415B-A856-29E31C69954BQ50677180-AACEF077-DF23-4777-A4A3-45D50D7A6363
P279
Q50254100-10720F4D-2D69-46C0-BEBC-C552EFE10F59Q50254573-874A3870-F2CC-4718-85FE-D4B9A8B3B071Q50255524-31233300-1398-4FE8-A5CC-2209DD51CC2BQ50255525-122FBEF5-EA1A-46FB-B349-43312ED3E489Q50255526-63F7036F-ACA4-4C52-8841-E8A07B04A2DCQ50255530-85D216FA-BD02-4C1A-81C8-6560AD768340Q50255535-15C2DF38-6C5E-4B48-8462-E5E4D9C22000Q50255536-BF817D70-1A04-4648-9570-BDF86F255692Q50255537-C85D8F76-2B7E-4EAB-A693-DA68B1517914Q50255540-C43E2DAB-A9D2-4A07-B6EB-A152B995C581Q50255541-9E58B001-BF2A-4C81-8C14-6F8246D9332CQ50255542-705AA431-0232-4C58-926C-D3A06BF2A48CQ50255543-C31A4FC2-EF30-4AEF-847F-29A7967732EDQ50255545-36874B62-2889-4B38-B7B7-0E0ACE8499BFQ50255546-FE210C02-4668-4F33-AA72-9B6AB3ACCCDCQ50255548-B67C9ECB-07FB-4BA2-99BD-69A001188E1DQ50255549-289F4CEC-2B23-4EA4-93E6-329C50926965Q50255587-161C4088-411A-41DC-B4D0-201D1ABC1D4CQ50255591-5ABF66D0-1EF6-44EA-84B0-5BAF9D9C9F87Q50255595-E49D504D-135F-4CCD-914E-C37DC5E4FBDFQ50255886-9DAA9A4C-F9E3-4CBD-BB71-D90199F3C720Q50270997-9B34201C-C6A1-453A-9101-B8BF746F3E1BQ50287676-9A295419-3FA8-4682-BE9A-DE8C0A71E178Q50288654-7508751A-EF28-4DBB-B9DF-FCA358198398Q50288656-1B087D74-33E0-422F-8562-9C971215F58AQ50297515-213973F2-DD04-4153-A353-4FDAFBE1D690Q50297518-05F17A13-5EE9-4F66-8C18-BC2F9A19AD6CQ50297522-0DC1AD09-9FD0-49E1-A552-2570A3B127F5Q50297551-61E99FAF-C58B-437F-A40D-8BE3730A9B92
P527
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Fibroblast growth factor receptor 1
@en
Fibroblast growth factor receptor 1
@nl
Receptor 1 fibroblastnog faktora rasta
@sh
type
label
Fibroblast growth factor receptor 1
@en
Fibroblast growth factor receptor 1
@nl
Receptor 1 fibroblastnog faktora rasta
@sh
altLabel
BFGFR
@en
FGFR1
@en
FGFR1/PLAG1 fusion
@en
FLT-2
@en
FMS-like tyrosine kinase 2
@en
N-sam
@en
bFGF-R-1
@en
basic fibroblast growth factor receptor 1
@en
fibroblast growth factor receptor 1
@en
fms-related tyrosine kinase 2
@en
prefLabel
Fibroblast growth factor receptor 1
@en
Fibroblast growth factor receptor 1
@nl
Receptor 1 fibroblastnog faktora rasta
@sh
P129
P361
P527
P637
P638
P680
P681
P682
P705
P352
P486
P637
P31
P352
P361
P486
P527
P637
NP_001167534
NP_001167535
NP_001167536
NP_001167537
NP_001167538
NP_001341296
NP_001341297
NP_001341298
NP_001341299
P638
P680
P681
P682
P702
P703
P705
ENSP00000327229
ENSP00000337247
ENSP00000340636
ENSP00000348537
ENSP00000380280
ENSP00000380292
ENSP00000380297
ENSP00000380302
ENSP00000392645
ENSP00000393312
P7260
8.A.23.1.7