about
P129
L-arginine 248 replaced with L-cysteineL-serine 249 replaced with L-cysteineglycine 370 replaced with L-cysteineL-serine 371 replaced with L-cysteineL-tyrosine 373 replaced with L-cysteineL-arginine 248 replaced with L-cysteine ser-577 ser-647 ser-648 ser-724 ser-760 ser-770 phosphorylatedglycine 370 replaced with L-cysteine ser-577 ser-647 ser-648 ser-724 ser-760 ser-770 phosphorylatedL-serine 371 replaced with L-cysteine ser-577 ser-647 ser-648 ser-724 ser-760 ser-770 phosphorylatedL-tyrosine 373 replaced with L-cysteine ser-577 ser-647 ser-648 ser-724 ser-760 ser-770 phosphorylatedglycine 380 replaced with L-arginineglycine 382 replaced with L-aspartic acidL-lysine 650 replaced with L-glutamic acidL-lysine 650 replaced with L-methionineL-lysine 650 replaced with L-asparagineL-lysine 650 replaced with L-glutamineL-lysine 650 replaced with L-threonineglycine 697 replaced with L-cysteineFGFR3 ser-unknown ser-unknown ser-unknown ser-unknown ser-unknown ser-unknown phosphorylatedL-proline 250 replaced with L-arginineL-proline 250 replaced with L-arginine ser-577 ser-647 ser-648 ser-724 ser-760 ser-770 phosphorylatedFGFR3 ser-577 ser-647 ser-648 ser-724 phosphorylatedFGFR3 ser-579 ser-649 ser-650 ser-726 ser-762 ser-772 phosphorylatedFGFR3 ser-577 ser-647 ser-648 ser-724 ser-760 ser-770 phosphorylatedL-serine 249 replaced with L-cysteine [plasma membrane]glycine 380 replaced with L-arginine [plasma membrane]glycine 382 replaced with L-aspartic acid [plasma membrane]L-lysine 650 replaced with L-glutamic acid [plasma membrane]L-lysine 650 replaced with L-methionine [plasma membrane]L-lysine 650 replaced with L-asparagine [plasma membrane]L-lysine 650 replaced with L-glutamine [plasma membrane]glycine 697 replaced with L-cysteine [plasma membrane]FGFR3 ser-unknown ser-unknown ser-unknown ser-unknown ser-unknown ser-unknown phosphorylated [plasma membrane]FGFR3 ser-577 ser-647 ser-648 ser-724 phosphorylated [plasma membrane]p-4Y FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane]p-4Y FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane]p-4Y FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane]p-4Y FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane]
P279
FGFR3 cysteine mutantsFGFR3 R248C mutant dimerFGFR3b S249C mutant dimerFGFR3 G370C mutant dimerFGFR3 S371C mutant dimerFGFR3 Y373C mutant dimerActivated FGFR3 R248C mutant dimerActivated FGFR3b S249C mutantActivated FGFR3 G370C mutantActivated FGFR3 S371C mutant dimerActivated FGFR3 Y373C mutant dimerFGFR3 point mutants with enhanced kinase activityFGFR3 G380R mutant dimerFGFR3 G382D mutant dimerFGFR3 K650E mutant dimerFGFR3 K650M mutant dimerFGFR3 K650N mutant dimerFGFR3 K650Q mutant dimerFGFR3 K650T mutant dimerFGFR3b G697C mutant dimerActivated FGFR3 G380R mutantActivated FGFR3 G382D mutantActivated FGFR3 K650E mutantActivated FGFR3 K650M mutantActivated FGFR3 K650N mutantActivated FGFR3 K650Q mutantActivated FGFR3 K650T mutantActivated FGFR3b G967CFGFR3c P250R mutant dimerp-6Y-FGFR3c P250R dimerFGFR3 (4;14) translocation mutantsFGFR3 795fs*139STOP mutant dimerActivated FGFR3 795fs*139STOP mutantFGFR3 fusionsFGFR3(23-758)-TACC3(549-838) dimerFGFR3(23-758)-TACC3(649-838) dimerFGFR3(23-760)-BAIAP2L1(18-522) dimerFGFR3(23-760)-TACC3(612-838) dimerFGFR3(23-760)-TACC3(647-838) dimerFGFR3(23-793)-TACC3(143-838) dimer
P527
P688
Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activationCell responses to FGFR3 signalling: growth, differentiation and apoptosisThe cell surface receptor FGFRL1 forms constitutive dimers that promote cell adhesionInsights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuitySustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis in the ATDC5 chondrogenic cell line via PLCgamma-activated STAT1Receptor specificity of the fibroblast growth factor familyFibroblast growth factor receptor 3 is a negative regulator of bone growthGeneration of Fgfr3 conditional knockout miceStructural Mimicry of A-Loop Tyrosine Phosphorylation by a Pathogenic FGF Receptor 3 MutationStructure of FGFR3 Transmembrane Domain Dimer: Implications for Signaling and Human Pathologies
P921
Q50369670-FCE99703-1773-49DA-86D9-9E3DD208D963Q50369671-1AEE6AC2-104F-41DF-AC12-F0E0E673EC6EQ50369672-CB19B767-885A-448A-91E5-1D81ADAF5DB0Q50369673-CE351B7F-2F05-4478-B703-C2E1F2AAA7FBQ50369674-777EBA52-E9FC-4AB2-BD29-DAB8D4057C98Q50369676-663FC8D0-55C9-49E0-91B5-0923908F5BCDQ50369678-C2C91BF8-8A83-4450-A8A8-20D31CF46165Q50369679-82C0C0A6-DBCF-48F1-82FA-122A13E6767DQ50369680-3A8D9FF2-D535-4AC0-B1D1-58AB18FBA9D4Q50369681-5C216778-3BE3-4DDC-A400-FD0B2DE372F7Q50369682-3A9E6076-C395-4FBD-AD1C-E4B8E3DBFB9DQ50369683-5CFDC5BF-1A63-4A9D-8806-60241059BC1EQ50369684-9ADB24F9-F3D0-48AC-BBD8-BF5F43026D7AQ50369685-2EFC2726-8DCD-40DE-B33E-88BD642E482FQ50369686-8D55D846-87F3-4F40-9F32-DD4BFEE50291Q50369687-2D9056C0-6810-41BA-8EE1-B071CC33E154Q50369688-F9E59879-C87D-428C-A1A9-8DC6E9EBDCB4Q50369695-B263377C-2801-473C-A360-0AE74A71B477Q50369698-52797432-B499-4E1C-82B4-CCF7FB410559Q50369699-A2B7C6D2-1A96-48A3-84F9-70A572ED1F12Q50369701-3795F2BB-0580-489C-8762-54165DE36026Q50369746-C2EFAF2A-0C79-4EC7-B72B-8EEE3D482A2EQ50369747-EFC8AE77-03A9-477E-BC64-41FCF2005B0CQ50677210-9085A20E-6207-49AC-85BD-33CEE7CA4371Q50677213-72313D38-36B7-4804-B1B8-F03F04A9F24FQ50677215-07B131F3-E14B-45F2-9763-C2AB64D3699AQ50677217-3376DC79-3B07-42B1-A3AC-A2CCA51E11E9Q50677219-C8A701DB-103D-4A5A-AB8C-DA14F48422E2Q50677222-8FC045A2-1656-4E17-ACEF-80636B8F3630Q50677223-51AC1A2C-DEA8-445B-AEF7-A9B16D9AD06AQ50677225-F8200BA3-9F6C-4059-B7A6-5548CD8C3367Q50677226-D1341C4A-BF16-44A6-9FAF-70035E42DDCBQ50677227-762E82AD-804D-4652-8202-3B08AD7FF63CQ50684276-4F761B49-070A-4735-8082-9E74C04C7E51Q50684279-3D1405AB-D14D-4230-A6A1-7EA3F63FC9AAQ50684281-C622AF2E-C8D6-4FC4-A922-FACC4ACC6A45Q50684284-B79AD914-986F-408A-91B1-BFED7D3F09F9
P279
Q50255699-E3022825-3B08-43F9-835A-48CF798272ADQ50255701-EF659C62-78FF-48FF-AB87-BA32067761F8Q50255702-636857E1-229C-45FF-B624-8DE8CDEF732CQ50255703-7B9E9387-E69E-4D2C-B666-3E32ABD2D8B5Q50255704-8E3E569A-277D-4A1A-BBF6-B0E5CC2CC536Q50255705-471705DA-317F-4BAC-ADD4-B3DF6414F7D4Q50255707-07017BCE-70CD-4D38-B2A4-1ECBD9CBEA8AQ50255708-025AED33-BC83-4170-A4ED-337D3A366CA8Q50255709-5EAEBCF3-FAB6-4A88-AB21-253D6322467FQ50255710-CFB4785C-C03C-47C5-9C19-B434A22AB7B2Q50255711-194645E7-D154-4169-BBED-1ADE1A8A0F8FQ50255712-0A642FAF-1974-49F8-A50B-E1171AA73C4FQ50255714-301EC5E8-1B36-450B-83E7-8EB1381A3A4DQ50255715-B3049B25-9B5C-4B63-8E09-27039889A83DQ50255716-4537EE83-0656-4ED6-ACD1-C40EFA9164E2Q50255717-C764FF87-0A54-4B22-BE3D-565C530D71B8Q50255719-EBD321D2-3BA5-49C8-B5B3-BFEACBAE2B55Q50255721-1267BC2F-56AE-49B0-BBD8-3AF2EF3A23E0Q50255722-88185292-0DD5-44BD-8046-199D24EE79A9Q50255723-09F79E0C-EECA-4272-AD4C-343F5891C509Q50255725-888E5A50-D0AE-4D09-A359-3447215126BCQ50255726-3858A7CB-5CD7-4923-A232-B2781F80BD9AQ50255727-2A4F66F0-49D8-42E8-BD50-FE8D6673EDFFQ50255728-BC746D92-6054-4D72-B7E1-A243FE43F0D1Q50255729-B4696248-5009-4752-8065-81F482BEC4C8Q50255730-2DEFEFEF-D99C-466B-975A-1B85057E5138Q50255732-AB5A1BC5-8106-4C3F-B6CB-D4813957219BQ50255733-D970096D-E2CE-44AA-BBBE-CC32316992C3Q50255736-232C1C6D-81D7-43D3-BB64-1C1BA74AE271Q50255738-EC0D1A6B-66C7-4EF8-BC6D-C5A33344CC66Q50255739-EF4B5A32-D5BE-430C-B0B0-B0312B43B319Q50255741-93061FAA-D5DC-4357-9FFE-6F11E82BB8B4Q50255744-4696C4C4-4931-4681-8D0C-3C9D2B38C3B4Q50255757-B42C6DE3-A259-4E8E-9335-7E30601EAC2AQ50255759-34D30971-A1FC-42B8-AA5D-53AA2C2E5657Q50255760-8AC1F218-C6CD-4EDD-BFE0-887A1EF41109Q50255761-3480D4D4-AAB9-4B71-A305-CAE58D56735EQ50255762-0254A5B6-65A1-4437-936C-16C1C6CD9F81Q50255763-A07CFCD9-761B-44AC-961A-A90B18AF9091Q50255764-3BD25B7A-37E2-4C44-9913-89EA7C87766F
P527
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Fibroblast growth factor receptor 3
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
FGFR3
@es
Fibroblast growth factor receptor 3
@en
Fibroblast growth factor receptor 3
@nl
Receptor 3 fibroblastnog faktora rasta
@sh
type
label
FGFR3
@es
Fibroblast growth factor receptor 3
@en
Fibroblast growth factor receptor 3
@nl
Receptor 3 fibroblastnog faktora rasta
@sh
altLabel
ACH
@en
CD333
@en
CEK2
@en
FGFR-3
@en
FGFR3
@en
HSFGFR3EX
@en
JTK4
@en
fibroblast growth factor receptor 3 variant 4
@en
fibroblast growth factor receptor 3
@en
fibroblast growth factor receptor 3-S
@en
prefLabel
FGFR3
@es
Fibroblast growth factor receptor 3
@en
Fibroblast growth factor receptor 3
@nl
Receptor 3 fibroblastnog faktora rasta
@sh
P361
P527
P637
P638
P680
P681
P682
P705
P352
P637
P129
P31
P352
P361
P527
P637
NP_001156685
NP_001341738
NP_001341739
XP_006713931
XP_006713932
XP_006713933
XP_006713934
XP_006713936
P638
P680
P681
P682
P702
P703
P705
ENSP00000231803
ENSP00000260795
ENSP00000339824
ENSP00000412903
ENSP00000414914
ENSP00000420533
ENSP00000427289
ENSP00000479472