about
Metagenomic approaches to exploit the biotechnological potential of the microbial consortia of marine sponges.Diversity of microbes associated with the marine sponge, Haliclona simulans, isolated from Irish waters and identification of polyketide synthase genes from the sponge metagenome.Marine metagenomics: strategies for the discovery of novel enzymes with biotechnological applications from marine environments.Phylogenetic diversity and antimicrobial activities of fungi associated with Haliclona simulans isolated from Irish coastal waters.Marine metagenomics: new tools for the study and exploitation of marine microbial metabolism.Aspects of the biosynthesis of non-aromatic fungal polyketides by iterative polyketide synthases.Functional metagenomic strategies for the discovery of novel enzymes and biosurfactants with biotechnological applications from marine ecosystems.Diversity and antimicrobial activities of microbes from two Irish marine sponges, Suberites carnosus and Leucosolenia sp.Pyrosequencing reveals diverse and distinct sponge-specific microbial communities in sponges from a single geographical location in Irish waters.Diversity and antibacterial activity of bacteria isolated from the coastal marine sponges Amphilectus fucorum and Eurypon major.Isolation identification and biochemical characterization of a novel halo-tolerant lipase from the metagenome of the marine sponge Haliclona simulansTargeted covalent inactivation of protein kinases by resorcylic acid lactone polyketides.Endoglucanase activities and growth of marine-derived fungi isolated from the sponge Haliclona simulans.Conversion of cyclic nonaketides to lovastatin and compactin by a lovC deficient mutant of Aspergillus terreus.Transformations of cyclic nonaketides by Aspergillus terreus mutants blocked for lovastatin biosynthesis at the lovA and lovC genes.6-Deoxyerythronolide B analogue production in Escherichia coli through metabolic pathway engineering.Precursor-directed biosynthesis of novel triketide lactones.Heterologous production of epothilone C and D in Escherichia coli.Isolation and analysis of bacteria with antimicrobial activities from the marine sponge Haliclona simulans collected from Irish waters.Evidence of bacteriophage-mediated horizontal transfer of bacterial 16S rRNA genes in the viral metagenome of the marine sponge Hymeniacidon perlevis.Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster.Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesisdelta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase is a rate limiting enzyme for penicillin production in Aspergillus nidulansACV synthetase: expression of amino acid activating domains of the Penicillium chrysogenum enzyme in Aspergillus nidulansThioesterase domain of delta-(l-alpha-Aminoadipyl)-l-cysteinyl-d-valine synthetase: alteration of stereospecificity by site-directed mutagenesisNurturing nature: engineering new antibiotics
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description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Jonathan Kennedy
@ast
Jonathan Kennedy
@en
Jonathan Kennedy
@es
Jonathan Kennedy
@nl
Jonathan Kennedy
@sl
جوناثان كينيدي
@ar
type
label
Jonathan Kennedy
@ast
Jonathan Kennedy
@en
Jonathan Kennedy
@es
Jonathan Kennedy
@nl
Jonathan Kennedy
@sl
جوناثان كينيدي
@ar
prefLabel
Jonathan Kennedy
@ast
Jonathan Kennedy
@en
Jonathan Kennedy
@es
Jonathan Kennedy
@nl
Jonathan Kennedy
@sl
جوناثان كينيدي
@ar
P106
P1153
7404197642
P21
P31
P496
0000-0002-9126-1198