about
Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repairTrue lies: the double life of the nucleotide excision repair factors in transcription and DNA repairSolution structure and self-association properties of the p8 TFIIH subunit responsible for trichothiodystrophyA new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group AMutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIHRescue of progeria in trichothiodystrophy by homozygous lethal Xpd allelesReconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7Ordered conformational changes in damaged DNA induced by nucleotide excision repair factors.p8/TTD-A as a repair-specific TFIIH subunit.Nucleotide excision repair driven by the dissociation of CAK from TFIIH.Sequential and ordered assembly of a large DNA repair complex on undamaged chromatin.Transcriptional activators stimulate DNA repair.Histone methyltransferase DOT1L drives recovery of gene expression after a genotoxic attack.Orchestral maneuvers at the damaged sites in nucleotide excision repair.DNA repair and transcriptional deficiencies caused by mutations in the Drosophila p52 subunit of TFIIH generate developmental defects and chromosome fragility.Regulatory interplay of Cockayne syndrome B ATPase and stress-response gene ATF3 following genotoxic stressDissection of the molecular defects caused by pathogenic mutations in the DNA repair factor XPC.ELL, a novel TFIIH partner, is involved in transcription restart after DNA repair.Molecular insights into the recruitment of TFIIH to sites of DNA damageThe long unwinding road: XPB and XPD helicases in damaged DNA opening.A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor.Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP.Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells.A small molecule screen identifies an inhibitor of DNA repair inducing the degradation of TFIIH and the chemosensitization of tumor cells to platinum.TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair.Transcription activities at 8-oxoG lesions in DNA.Unified promoter opening steps in eukaryotic gene expression.Cockayne's Syndrome A and B Proteins Regulate Transcription Arrest after Genotoxic Stress by Promoting ATF3 Degradation.p52 Mediates XPB function within the transcription/repair factor TFIIH.Transcription without XPB Establishes a Unified Helicase-Independent Mechanism of Promoter Opening in Eukaryotic Gene Expression.Revisiting the Function of CDK7 in Transcription by Virtue of a Recently Described TFIIH Kinase Inhibitor.XPC is an RNA polymerase II cofactor recruiting ATAC to promoters by interacting with E2F1.Two sides of the same coin: TFIIH complexes in transcription and DNA repair.TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcriptionFunctional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expressionDistinct roles for the helicases of TFIIH in transcript initiation and promoter escapePoly (ADP-ribose) glycohydrolase regulates retinoic acid receptor-mediated gene expressionActivation of P-TEFb by RBM7: To Live or Let DieDNA repair complex licenses acetylation of H2A.Z.1 by KAT2A during transcriptionConducting the CTD orchestra
P50
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P50
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