about
XPF protein levels determine sensitivity of malignant melanoma cells to oxaliplatin chemotherapy: suitability as a biomarker for patient selection.NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug.Triazene compounds in the treatment of acute myeloid leukemia: a short review and a case report.Placenta growth factor and neuropilin-1 collaborate in promoting melanoma aggressiveness.Influence of fatty acid synthase inhibitor orlistat on the DNA repair enzyme O6-methylguanine-DNA methyltransferase in human normal or malignant cells in vitro.Cilengitide downmodulates invasiveness and vasculogenic mimicry of neuropilin 1 expressing melanoma cells through the inhibition of αvβ5 integrin.Platelet-derived growth factor C and calpain-3 are modulators of human melanoma cell invasiveness.Neuropilin-1 expression promotes invasiveness of melanoma cells through vascular endothelial growth factor receptor-2-dependent and -independent mechanisms.Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: role in tumour progression.Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.Role of the mismatch repair system and p53 in the clastogenicity and cytotoxicity induced by bleomycin.In vitro antitumour activity of resveratrol in human melanoma cells sensitive or resistant to temozolomide.Biallelic somatic inactivation of the mismatch repair gene MLH1 in a primary skin melanoma.High-frequency microsatellite instability is associated with defective DNA mismatch repair in human melanoma.Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytesIn vitro combined effects of a triazene compound and interferon-beta on natural immunity against lymphoblastoid cells: studies at effector and target cell level.O6-(4-bromothenyl)guanine (PaTrin-2), a novel inhibitor of O6-alkylguanine DNA alkyl-transferase, increases the inhibitory activity of temozolomide against human acute leukaemia cells in vitro.Concomitant activation of Wnt pathway and loss of mismatch repair function in human melanoma.Thrombospondin-1 is part of a Slug-independent motility and metastatic program in cutaneous melanoma, in association with VEGFR-1 and FGF-2.The effect of O6-alkylguanine-DNA alkyltransferase and mismatch repair activities on the sensitivity of human melanoma cells to temozolomide, 1,3-bis(2-chloroethyl)1-nitrosourea, and cisplatin.Role of mismatch repair in the induction of chromosomal aberrations and sister chromatid exchanges in cells treated with different chemotherapeutic agents.A proangiogenic peptide derived from vascular endothelial growth factor receptor-1 acts through alpha5beta1 integrin.Inhibition of endothelial cell migration and angiogenesis by a vascular endothelial growth factor receptor-1 derived peptide.BCG-infected adherent mononuclear cells release cytokines that regulate group 1 CD1 molecule expression.Immunization of stage IV melanoma patients with Melan-A/MART-1 and gp100 peptides plus IFN-alpha results in the activation of specific CD8(+) T cells and monocyte/dendritic cell precursors.Analysis of candidate genes through a proteomics-based approach in primary cell lines from malignant melanomas and their metastases.Molecular alterations at chromosome 9p21 in melanocytic naevi and melanomaEffects of Lonidamine on murine and human tumor cells in vitro. A morphological and biochemical studyHigh expression of the mismatch repair protein MSH6 is associated with poor patient survival in melanomaIn vitro antitumor activity of 3′-desamino-3′(2-methoxy-4-morpholinyl) doxorubicin on human melanoma cells sensitive or resistant to triazene compoundsO6-alkylguanine-DNA alkyltransferase activity in blasts obtained from patients with myelogenous or lymphocytic leukemiaEffect of hydrocortisone on human natural killer activity and its modulation by beta interferonComparative studies between in vitro and in vivo effects of human beta-interferon on natural killer activity and its relevance to immunochemotherapyCombined effects of 5-fluorouracil and beta interferon on HBL-100 human breast cancer cells in vitroChanges of immunological patterns of human cancer cells treated in vitro with a triazene compoundThe effect of gossypol and Lonidamine on electron transport in Ehrlich ascites tumor mitochondriaEnergy metabolism of normal and lonidamine-treated Sertoli cells of ratsThe effect of the association of Gossypol and Lonidamine on the energy metabolism of Ehrlich ascites tumor cellsPolymorphisms of GSTM1 and GSTT1, sun exposure and the risk of melanoma: a case-control study
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