MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

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MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

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MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

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Item

label

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

@en

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

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MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

@en

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

@nl

P1476

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

@en

P2093

Adrián César-Razquin

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Alexey Stukalov

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André C Müller

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Anna Skucha

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Balázs Győrffy

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Bin Lu

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Christopher R Vakoc

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Mareike Roth

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Martin Aichinger

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Matthias Muhar

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P2860

Viral immune modulators perturb the human molecular network by common and unique strategies

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription

Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)

The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis

Multiplex genome engineering using CRISPR/Cas systems

Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner

Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance

Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia.

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia

P2888

s41467-018-04329-y

P304

1983

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P31

scholarly article

P356

10.1038/S41467-018-04329-Y

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P407

English

P433

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P478

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P50

P577

2018-05-18T00:00:00Z

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P6179

1103975511

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P698

29777171

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P932

5959866

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