about
From self-assembled vesicles to protocellsThe RNA World as a Model System to Study the Origin of LifeDissecting temporal and spatial control of cytokinesis with a myosin II InhibitorSelection for replicases in protocellsRNA catalysis in model protocell vesiclesEffect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replicationInhibition of bacterial conjugation by phage M13 and its protein g3p: quantitative analysis and modelA kinetic study of the growth of fatty acid vesicles.Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles.The emergence of competition between model protocells.GE Prize-winning essay. The emergence of cells during the origin of life.Quadruplet codons: one small step for a ribosome, one giant leap for proteins: an expanded genetic code could address fundamental questions about algorithmic information, biological function, and the origins of life.The prebiotic evolutionary advantage of transferring genetic information from RNA to DNAComputational analysis of fitness landscapes and evolutionary networks from in vitro evolution experiments.From prelife to life: how chemical kinetics become evolutionary dynamics.A population-based experimental model for protein evolution: effects of mutation rate and selection stringency on evolutionary outcomes.Shrink-wrap vesicles.Comprehensive experimental fitness landscape and evolutionary network for small RNA.Genetic drift suppresses bacterial conjugation in spatially structured populations.Experimental fitness landscapes to understand the molecular evolution of RNA-based life.Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences.Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequences.From underwear to non-equilibrium thermodynamics: physical chemistry informs the origin of life.Origin of Life: Protocells Red in Tooth and Claw.Molecular crowding and early evolution.Prebiotic chemistry: Replicating towards complexity.The paradox of dual roles in the RNA world: resolving the conflict between stable folding and templating ability.Analysis of Evolutionarily Independent Protein-RNA Complexes Yields a Criterion to Evaluate the Relevance of Prebiotic Scenarios.Mapping a Systematic Ribozyme Fitness Landscape Reveals a Frustrated Evolutionary Network for Self-Aminoacylating RNA.Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequencesPromiscuous Ribozymes and Their Proposed Role in Prebiotic EvolutionRapid Colorimetric Detection of Bacterial Species through the Capture of Gold Nanoparticles by Chimeric PhagesEffect of UV Radiation on Fluorescent RNA Aptamers' Functional and Templating AbilityControlled phage therapy by photothermal ablation of specific bacterial species using gold nanorods targeted by chimeric phagesImproved single-swab sample preparation for recovering bacterial and phage DNA from human skin and wound microbiomesMicrobial predictors of healing and short-term effect of debridement on the microbiome of chronic woundsEasyDIVER: A Pipeline for Assembling and Counting High-Throughput Sequencing Data from In Vitro Evolution of Nucleic Acids or Peptides
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Irene A Chen
@ast
Irene A Chen
@en
Irene A Chen
@es
Irene A Chen
@nl
type
label
Irene A Chen
@ast
Irene A Chen
@en
Irene A Chen
@es
Irene A Chen
@nl
prefLabel
Irene A Chen
@ast
Irene A Chen
@en
Irene A Chen
@es
Irene A Chen
@nl
P106
P21
P31
P496
0000-0001-6040-7927