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The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAMThe related neuronal endosomal proteins NEEP21 (Nsg1) and P19 (Nsg2) have divergent expression profiles in vivo.Doublecortin (DCX) mediates endocytosis of neurofascin independently of microtubule binding.Different Doublecortin (DCX) Patient Alleles Show Distinct Phenotypes in Cultured Neurons: EVIDENCE FOR DIVERGENT LOSS-OF-FUNCTION AND "OFF-PATHWAY" CELLULAR MECHANISMS.The neurotrophin receptor signaling endosome: Where trafficking meets signaling.Studying endosomes in cultured neurons by live-cell imaging.Ctip2-, Satb2-, Prox1-, and GAD65-Expressing Neurons in Rat Cultures: Preponderance of Single- and Double-Positive Cells, and Cell Type-Specific Expression of Neuron-Specific Gene Family Members, Nsg-1 (NEEP21) and Nsg-2 (P19)Maturational conversion of dendritic early endosomes and their roles in L1-mediated axon growthDoublecortin (Dcx) family proteins regulate filamentous actin structure in developing neurons.Harnessing the power of the endosome to regulate neural development.Mechanisms of polarized membrane trafficking in neurons -- focusing in on endosomes.Endocytosis and endosomes at the crossroads of regulating trafficking of axon outgrowth-modifying receptors.Neuronal early endosomes require EHD1 for L1/NgCAM traffickingAlterations of EHD1/EHD4 protein levels interfere with L1/NgCAM endocytosis in neurons and disrupt axonal targetingInhibition of sphingolipid synthesis affects kinetics but not fidelity of L1/NgCAM transport along direct but not transcytotic axonal pathways.Myelin under construction -- teamwork required.Recycling endosomes of polarized epithelial cells actively sort apical and basolateral cargos into separate subdomainsPathway selection to the axon depends on multiple targeting signals in NgCAM.Compartmentalizing the neuronal plasma membrane from axon initial segments to synapses.Acid indigestion in the endosome: linking signaling dysregulation to neurodevelopmental disorders.Transcytosis of NgCAM in epithelial cells reflects differential signal recognition on the endocytic and secretory pathways.The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes.A new Rab7 effector controls phosphoinositide conversion in endosome maturation.TrkA Bumps into Its Future Self.Introduction to the special issue on membrane trafficking in neurons.Transcytosis of TrkA leads to diversification of dendritic signaling endosomes.Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomesA dominant dendrite phenotype caused by the disease-associated G253D mutation in doublecortin (DCX) is not due to its endocytosis defectNestin in immature embryonic neurons regulates axon growth cone morphology and Sema3a sensitivityA dominant dendrite phenotype caused by the disease-associated G253D mutation in doublecortin (DCX) is not due to its endocytosis defectCover ImageBulk degradation of dendritic cargos requires Rab7-dependent transport in Rab7-positive/LAMP1-negative endosomes to somatic lysosomesSignalling from Endosomes and ExosomesThe Endolysosomal System and Proteostasis: From Development to DegenerationNeuron-Specific Gene 2 (NSG2) Encodes an AMPA Receptor Interacting Protein That Modulates Excitatory Neurotransmissionp75NTR and DR6 Regulate Distinct Phases of Axon Degeneration Demarcated by Spheroid RuptureNestin selectively facilitates the phosphorylation of the Lissencephaly-linked protein doublecortin (DCX) by cdk5/p35 to regulate growth cone morphology and Sema3a sensitivity in developing neuronsIntermediate filaments in developing neurons: Beyond structure
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Bettina Winckler
@ast
Bettina Winckler
@en
Bettina Winckler
@es
Bettina Winckler
@nl
type
label
Bettina Winckler
@ast
Bettina Winckler
@en
Bettina Winckler
@es
Bettina Winckler
@nl
prefLabel
Bettina Winckler
@ast
Bettina Winckler
@en
Bettina Winckler
@es
Bettina Winckler
@nl
P106
P31
P496
0000-0002-7924-9313