about
Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replicationStructure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy.In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replicationPfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome IntegrityUnwinding the functions of the Pif1 family helicases.The Pif1 family helicase Pfh1 facilitates telomere replication and has an RPA-dependent role during telomere lengthening.The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past G-quadruplex motifs to prevent DNA damageDNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase.The functions of the multi-tasking Pfh1Pif1 helicase.G-rich telomeric and ribosomal DNA sequences from the fission yeast genome form stable G-quadruplex DNA structures in vitro and are unwound by the Pfh1 DNA helicaseEvidence for lesion bypass by yeast replicative DNA polymerases during DNA damage.Design and Synthesis of 2,2'-Diindolylmethanes to Selectively Target Certain G-Quadruplex DNA Structures.Identification of Compounds that Selectively Stabilize Specific G-Quadruplex Structures by Using a Thioflavin T-Displacement Assay as a Tool.The Pif1 signature motif of Pfh1 is necessary for both protein displacement and helicase unwinding activities, but is dispensable for strand-annealing activitySynthesis of phenanthridine spiropyrans and studies of their effects on G-quadruplex DNAFlexible Versus Rigid G-Quadruplex DNA Ligands: Synthesis of Two Series of Bis-indole Derivatives and Comparison of Their Interactions with G-Quadruplex DNAA Light-up Logic Platform for Selective Recognition of Parallel G-Quadruplex Structures via Disaggregation-Induced EmissionQuinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G-Quadruplex StabilizationIdentification of putative G-quadruplex DNA structures in S. pombe genome by quantitative PCR stop assayA site-specific self-assembled light-up rotor probe for selective recognition and stabilization of c-MYC G-quadruplex DNA
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Nasim Sabouri
@ast
Nasim Sabouri
@en
Nasim Sabouri
@es
Nasim Sabouri
@nl
type
label
Nasim Sabouri
@ast
Nasim Sabouri
@en
Nasim Sabouri
@es
Nasim Sabouri
@nl
prefLabel
Nasim Sabouri
@ast
Nasim Sabouri
@en
Nasim Sabouri
@es
Nasim Sabouri
@nl
P106
P108
P1153
8131224700
P31
P496
0000-0002-4541-7702