about
Mitochondrial glutathione: features, regulation and role in diseasejkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegansTrafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alphaGD3 synthase overexpression sensitizes hepatocarcinoma cells to hypoxia and reduces tumor growth by suppressing the cSrc/NF-kappaB survival pathway.Mitochondrial glutathione, a key survival antioxidant.Redox control of liver function in health and diseaseProbiotic sonicates selectively induce mucosal immune cells apoptosis through ceramide generation via neutral sphingomyelinaseSpecific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione.Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell deathAcidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesisIdentification and functional analysis of mutations in FAD-binding domain of mitochondrial glycerophosphate dehydrogenase in caucasian patients with type 2 diabetes mellitus.Growth arrest-specific protein 6 is hepatoprotective against murine ischemia/reperfusion injury.Effect of chronic ethanol feeding on glutathione and functional integrity of mitochondria in periportal and perivenous rat hepatocytes.Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma.Angiogenin secretion from hepatoma cells activates hepatic stellate cells to amplify a self-sustained cycle promoting liver cancer.Glycosphingolipids and mitochondria: role in apoptosis and disease.Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation.Glycosphingolipids and cell death: one aim, many waysSphingolipids and cell death.Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitisPharmacological modulation of sphingolipids and role in disease and cancer cell biology.Reactive oxygen species mediate liver injury through parenchymal nuclear factor-kappaB inactivation in prolonged ischemia/reperfusion.ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation.Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress.Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis.Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis.Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma.Critical role of mitochondrial glutathione in the survival of hepatocytes during hypoxia.The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading.Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase.Cell autonomous apoptosis defects in acid sphingomyelinase knockout fibroblasts.Ganglioside GD3 sensitizes human hepatoma cells to cancer therapy.Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-kappaB activation.Bone morphogenetic protein-9/activin-like kinase 1 axis a new target for hepatic regeneration and fibrosis treatment in liver injury.Transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase by ionizing radiation.Neutral sphingomyelinase-induced ceramide triggers germinal vesicle breakdown and oxidant-dependent apoptosis in Xenopus laevis oocytes.Antiapoptotic BCL-2 proteins determine sorafenib/regorafenib resistance and BH3-mimetic efficacy in hepatocellular carcinoma.Orthoxenografts of testicular germ cell tumors demonstrate genomic changes associated with cisplatin resistance and identify PDMP as a re-sensitizing agent.Stromal interaction molecule 2 (STIM2) is frequently overexpressed in colorectal tumors and confers a tumor cell growth suppressor phenotype.
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Albert Morales
@ast
Albert Morales
@en
Albert Morales
@es
Albert Morales
@nl
type
label
Albert Morales
@ast
Albert Morales
@en
Albert Morales
@es
Albert Morales
@nl
prefLabel
Albert Morales
@ast
Albert Morales
@en
Albert Morales
@es
Albert Morales
@nl
P1053
E-2988-2013
P106
P1153
7202369612
P21
P31
P496
0000-0001-8702-2269