about
Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalonFunctional characterization of promoter variants of the adiponectin gene complemented by epidemiological dataEffects of TWEAK (TNF superfamily member 12) on differentiation, metabolism, and secretory function of human primary preadipocytes and adipocytes.Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation.Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146Medium-chain dicarboxylic acylcarnitines as markers of n-3 PUFA-induced peroxisomal oxidation of fatty acids.Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis.Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes.Myosin light chain 1 atrial isoform (MLC1A) is expressed in pre-B cells under control of the BOB.1/OBF.1 coactivatorExpression of the aldehyde dehydrogenase 2-like gene is controlled by BOB.1/OBF.1 in B lymphocytes.Defective octamer-dependent transcription is responsible for silenced immunoglobulin transcription in Reed-Sternberg cells.Octamer-dependent transcription in T cells is mediated by NFAT and NF-κB.LIGHT (TNFSF14) inhibits adipose differentiation without affecting adipocyte metabolism.Role of the adipocyte-specific NF-κB activity in the regulation of IP-10 and T cell migration.Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis.5-Hydroxymethylcytosine Remodeling Precedes Lineage Specification during Differentiation of Human CD4(+) T Cells.Peripheral monocytes of obese women display increased chemokine receptor expression and migration capacity.Genetic variants in the leukemia-associated Rho guanine nucleotide exchange factor (ARHGEF12) gene are not associated with T2DM and related parameters in Caucasians (KORA study).Postprandial activation of metabolic and inflammatory signalling pathways in human peripheral mononuclear cells.A common atopy-associated variant in the Th2 cytokine locus control region impacts transcriptional regulation and alters SMAD3 and SP1 bindingApplication of differential cDNA screening techniques to the identification of unique gene expression in tumours and lymphocytesThe BOB.1 / OBF.1 co-activator is essential for octamer-dependent transcription in B cellsDynamic modelling of an ACADS genotype in fatty acid oxidation - Application of cellular models for the analysis of common genetic variants
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Helmut Laumen
@ast
Helmut Laumen
@en
Helmut Laumen
@es
Helmut Laumen
@nl
type
label
Helmut Laumen
@ast
Helmut Laumen
@en
Helmut Laumen
@es
Helmut Laumen
@nl
prefLabel
Helmut Laumen
@ast
Helmut Laumen
@en
Helmut Laumen
@es
Helmut Laumen
@nl
P106
P21
P31
P496
0000-0002-5885-5242