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β-arrestin-dependent activation of the cofilin pathway is required for the scavenging activity of the atypical chemokine receptor D6Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signalingNeutropenic Mice Provide Insight into the Role of Skin-Infiltrating Neutrophils in the Host Protective Immunity against Filarial Infective LarvaeEvidence for a role of CRM1 in signal-mediated nuclear protein exportNeutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrowThe chemokine CXCL12 is essential for the clearance of the filaria Litomosoides sigmodontis in resistant miceCXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome.Chromothriptic cure of WHIM syndrome.An atypical addition to the chemokine receptor nomenclature: IUPHAR Review 15.The CXCL12/CXCR4 Signaling Pathway: A New Susceptibility Factor in Human Papillomavirus PathogenesisDescription and outcome of a cohort of 8 patients with WHIM syndrome from the French Severe Chronic Neutropenia RegistryHigh frequency of GATA2 mutations in patients with mild chronic neutropenia evolving to MonoMac syndrome, myelodysplasia, and acute myeloid leukemia.CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses.International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors.Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement.CXCL12/CXCR4-axis dysfunctions: Markers of the rare immunodeficiency disorder WHIM syndrome.The relevance of the chemokine receptor ACKR3/CXCR7 on CXCL12-mediated effects in cancers with a focus on virus-related cancers.CXCR4 dysfunction in non-alcoholic steatohepatitis in mice and patients.MIF interacts with CXCR7 to promote receptor internalization, ERK1/2 and ZAP-70 signaling, and lymphocyte chemotaxis.CD4 and CCR5 constitutively interact at the plasma membrane of living cells: a confocal fluorescence resonance energy transfer-based approach.Mutation of the DRY motif reveals different structural requirements for the CC chemokine receptor 5-mediated signaling and receptor endocytosis.Interaction of chemokine receptor CXCR4 in monomeric and dimeric state with its endogenous ligand CXCL12: coarse-grained simulations identify differences.CD4 interacts constitutively with multiple CCR5 at the plasma membrane of living cells. A fluorescence recovery after photobleaching at variable radii approach.Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and G(alpha)(i) activation.The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts.Symptomatic Improvement in Human Papillomavirus-Induced Epithelial Neoplasia by Specific Targeting of the CXCR4 Chemokine Receptor.Palmitoylation-dependent control of degradation, life span, and membrane expression of the CCR5 receptor.A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate.CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling.Glucocorticoid-Induced Leucine Zipper Protein Controls Macropinocytosis in Dendritic Cells.Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions.[WHIM syndrome: on the track of an interplay between human papillomavirus and the CXCL12 chemokine].Two cases of disseminated Mycobacterium avium infection associated with a new immunodeficiency syndrome related to CXCR4 dysfunctions.Complementary methods provide evidence for the expression of CXCR7 on human B cells.Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and Gαi activation.Natural history of GATA2 deficiency in a survey of 79 French and Belgian patientsWHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12OMIP-048 MC: Quantification of calcium sensors and channels expression in lymphocyte subsets by mass cytometryGlucocorticoid-Induced Leucine Zipper Enhanced Expression in Dendritic Cells Is Sufficient To Drive Regulatory T Cells Expansion In Vivo
P50
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P50
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wetenschapper
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հետազոտող
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Françoise Bachelerie
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Françoise Bachelerie
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Françoise Bachelerie
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Françoise Bachelerie
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Françoise Bachelerie
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P1053
F-8823-2013
P106
P31
P496
0000-0002-0399-3277