about
Conformational changes during pore formation by the perforin-related protein pleurotolysinCrystal structure of carbapenem synthase (CarC)A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocationMechanism of eIF6-mediated Inhibition of Ribosomal Subunit JoiningStructure of the Drosophila Apoptosome at 6.9 Å ResolutionChanges in Apaf-1 Conformation That Drive Apoptosome AssemblyStructure of a translocation signal domain mediating conjugative transfer by type IV secretion systemsThe Structure of Herpesvirus Fusion Glycoprotein B-Bilayer Complex Reveals the Protein-Membrane and Lateral Protein-Protein InteractionCombined approaches to flexible fitting and assessment in virus capsids undergoing conformational changeMutations in SLC12A5 in epilepsy of infancy with migrating focal seizures.Novel Missense Mutation A789V in IQSEC2 Underlies X-Linked Intellectual Disability in the MRX78 FamilyAllosteric signalling in the outer membrane translocation domain of PapC usher.Refinement of atomic models in high resolution EM reconstructions using Flex-EM and local assessment.A novel dominant hyperekplexia mutation Y705C alters trafficking and biochemical properties of the presynaptic glycine transporter GlyT2Photo-antagonism of the GABAA receptor.TEMPy: a Python library for assessment of three-dimensional electron microscopy density fitsPREDICT modeling and in-silico screening for G-protein coupled receptors.Structure of an apoptosome-procaspase-9 CARD complex.TUBA1A mutations cause wide spectrum lissencephaly (smooth brain) and suggest that multiple neuronal migration pathways converge on alpha tubulins.Conformational States of macromolecular assemblies explored by integrative structure calculation.Collaborative computational project for electron cryo-microscopy.Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins.Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin.Two distinct trimeric conformations of natively membrane-anchored full-length herpes simplex virus 1 glycoprotein B.Outcome of the First wwPDB Hybrid/Integrative Methods Task Force WorkshopHVint: A Strategy for Identifying Novel Protein-Protein Interactions in Herpes Simplex Virus Type 1Distinct phenotypes in zebrafish models of human startle disease.Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism.Integrative modelling of cellular assemblies.Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease.Improved metrics for comparing structures of macromolecular assemblies determined by 3D electron-microscopy.The Importance of Non-accessible Crosslinks and Solvent Accessible Surface Distance in Modeling Proteins with Restraints From Crosslinking Mass Spectrometry.Mapping a molecular link between allosteric inhibition and activation of the glycine receptor.γ-TEMPy: Simultaneous Fitting of Components in 3D-EM Maps of Their Assembly Using a Genetic Algorithm.A fast mathematical programming procedure for simultaneous fitting of assembly components into cryoEM density maps.CHOYCE: a web server for constrained homology modelling with cryoEM maps.Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.Correction: Allosteric signalling in the outer membrane translocation domain of PapC usher.Molecular dynamics simulations of the acyl-enzyme and the tetrahedral intermediate in the deacylation step of serine proteases.
P50
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P50
description
researcher ORCID ID = 0000-0002-8185-1215
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wetenschapper
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name
Maya Topf
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Maya Topf
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Maya Topf
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Maya Topf
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Maya Topf
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Maya Topf
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Maya Topf
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Maya Topf
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Maya Topf
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Maya Topf
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Maya Topf
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Maya Topf
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P106
P31
P496
0000-0002-8185-1215