Identification of a Novel Arabinofuranosyltransferase AftB Involved in a Terminal Step of Cell Wall Arabinan Biosynthesis in Corynebacterianeae, such asCorynebacterium glutamicumandMycobacterium tuberculosis
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targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysisReconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donorsGalactosyl transferases in mycobacterial cell wall synthesisBiosynthesis of mycobacterial arabinogalactan: identification of a novel alpha(1-->3) arabinofuranosyltransferasePhylogenetic framework and molecular signatures for the main clades of the phylum Actinobacteria.The C-Terminal Domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC Is a Lectin-Like Carbohydrate Binding ModulePpm1-encoded polyprenyl monophosphomannose synthase activity is essential for lipoglycan synthesis and survival in mycobacteriaIdentification of an alpha(1-->6) mannopyranosyltransferase (MptA), involved in Corynebacterium glutamicum lipomanann biosynthesis, and identification of its orthologue in Mycobacterium tuberculosisBiochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetaseTetrahydrolipstatin inhibition, functional analyses, and three-dimensional structure of a lipase essential for mycobacterial viabilityCharacterization of the Corynebacterium glutamicum deltapimB' deltamgtA double deletion mutant and the role of Mycobacterium tuberculosis orthologues Rv2188c and Rv0557 in glycolipid biosynthesisThe identification and location of succinyl residues and the characterization of the interior arabinan region allow for a model of the complete primary structure of Mycobacterium tuberculosis mycolyl arabinogalactanA truncated lipoglycan from mycobacteria with altered immunological properties.A deficiency in arabinogalactan biosynthesis affects Corynebacterium glutamicum mycolate outer membrane stabilityThe cell envelope glycoconjugates of Mycobacterium tuberculosisLipoarabinomannan biosynthesis in Corynebacterineae: the interplay of two α(1→2)-mannopyranosyltransferases MptC and MptD in mannan branching.Insights into the microbial degradation of rubber and gutta-percha by analysis of the complete genome of Nocardia nova SH22aLipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host-pathogen interactionExposure of mycobacteria to cell wall-inhibitory drugs decreases production of arabinoglycerolipid related to Mycolyl-arabinogalactan-peptidoglycan metabolism.Defining mycobacteria: Shared and specific genome features for different lifestylesThe lipoprotein LpqW is essential for the mannosylation of periplasmic glycolipids in Corynebacteria.Targeting the formation of the cell wall core of M. tuberculosis.Identification of a novel alpha(1-->6) mannopyranosyltransferase MptB from Corynebacterium glutamicum by deletion of a conserved gene, NCgl1505, affords a lipomannan- and lipoarabinomannan-deficient mutant.Biosynthesis of D-arabinose in mycobacteria - a novel bacterial pathway with implications for antimycobacterial therapy.Synthesis of deoxygenated alpha(1-->5)-linked arabinofuranose disaccharides as substrates and inhibitors of arabinosyltransferases of Mycobacterium tuberculosisPartial redundancy in the synthesis of the D-arabinose incorporated in the cell wall arabinan of Corynebacterineae.AftD, a novel essential arabinofuranosyltransferase from mycobacteria.Chapter 2: Biogenesis of the cell wall and other glycoconjugates of Mycobacterium tuberculosis.Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan.Arabinogalactan and lipoarabinomannan biosynthesis: structure, biogenesis and their potential as drug targets.Targeting the mycobacterial envelope for tuberculosis drug development.The Mycobacterial Cell Wall--Peptidoglycan and Arabinogalactan.Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target.The Antituberculosis Drug Ethambutol Selectively Blocks Apical Growth in CMN Group Bacteria.Identification of a Membrane Protein Required for Lipomannan Maturation and Lipoarabinomannan Synthesis in Corynebacterineae.Comparing Galactan Biosynthesis in Mycobacterium tuberculosis and Corynebacterium diphtheriae.Microbial Offense vs Host Defense: Who Controls the TB Granuloma?Development of new antituberculous agents based on new drug targets and structure-activity relationship.Impact of LytR-CpsA-Psr Proteins on Cell Wall Biosynthesis in Corynebacterium glutamicum.GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis.
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Identification of a Novel Arabinofuranosyltransferase AftB Involved in a Terminal Step of Cell Wall Arabinan Biosynthesis in Corynebacterianeae, such asCorynebacterium glutamicumandMycobacterium tuberculosis
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im März 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в березні 2007
@uk
name
Identification of a Novel Arab ...... mandMycobacterium tuberculosis
@en
Identification of a Novel Arab ...... mandMycobacterium tuberculosis
@nl
type
label
Identification of a Novel Arab ...... mandMycobacterium tuberculosis
@en
Identification of a Novel Arab ...... mandMycobacterium tuberculosis
@nl
prefLabel
Identification of a Novel Arab ...... mandMycobacterium tuberculosis
@en
Identification of a Novel Arab ...... mandMycobacterium tuberculosis
@nl
P2093
P2860
P356
P1476
Identification of a novel arab ...... and Mycobacterium tuberculosis
@en
P2093
Helen L Birch
Hermann Sahm
Lothar Eggeling
Mathias Seidel
P2860
P304
14729-14740
P356
10.1074/JBC.M700271200
P407
P577
2007-03-26T00:00:00Z