Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells

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Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells

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im Januar 2018 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована у 2018

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Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells

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Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells

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Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells

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Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells

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Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells

@en

Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells

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P1476

Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells

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P2093

Chiaki Kobayashi

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Junko H Ohyashiki

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Satoshi Imanishi

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Tomohiko Ohta

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P2860

The Polycomb group protein EZH2 directly controls DNA methylation

The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

Comprehensive mapping of the effects of azacitidine on DNA methylation, repressive/permissive histone marks and gene expression in primary cells from patients with MDS and MDS-related disease.

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.

Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine.

ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin.

DNA methyltransferase inhibition may limit cancer cell growth by disrupting ribosome biogenesis

RNA-dependent inhibition of ribonucleotide reductase is a major pathway for 5-azacytidine activity in acute myeloid leukemia.

Five-aza-2'-deoxycytidine-induced hypomethylation of cholesterol 25-hydroxylase gene is responsible for cell death of myelodysplasia/leukemia cells.

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1166

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scholarly article

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10.3389/FPHAR.2018.01166

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English

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Tomohiro Umezu

Kazuma Ohyashiki

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2018-01-01T00:00:00Z

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P698

30386240

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P921

Farmakologi

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6198088

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