Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy

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Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy

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http://www.wikidata.org/entity/Q58776882

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im Juni 2018 veröffentlichter wissenschaftlicher Artikel

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scientific article published on 07 June 2018

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wetenschappelijk artikel

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наукова стаття, опублікована у вересні 2018

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Impaired mitochondrial activit ...... tients undergoing chemotherapy

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Impaired mitochondrial activit ...... tients undergoing chemotherapy

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Impaired mitochondrial activit ...... tients undergoing chemotherapy

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Impaired mitochondrial activit ...... tients undergoing chemotherapy

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Impaired mitochondrial activit ...... tients undergoing chemotherapy

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Impaired mitochondrial activit ...... tients undergoing chemotherapy

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Impaired mitochondrial activit ...... tients undergoing chemotherapy

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Constance C F M J Baaten

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Erik A M Beckers

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Floor C J I Moenen

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Frauke Swieringa

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Graham P Holloway

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Harry F G Heijnen

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Hugo Ten Cate

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Johan W M Heemskerk

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René van Oerle

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Rick J H Wetzels

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P2860

Prophylactic platelet transfusion for prevention of bleeding in patients with haematological disorders after chemotherapy and stem cell transplantation

Do basic laboratory tests or clinical observations predict bleeding in thrombocytopenic oncology patients? A reevaluation of prophylactic platelet transfusions.

Assessment of an immature platelet fraction (IPF) in peripheral thrombocytopenia.

Relationship between platelet count and bleeding risk in thrombocytopenic patients.

Multiple platelet defects identified by flow cytometry at diagnosis in acute myeloid leukaemia.

Chemotherapy-induced thrombocytopenia derives from the selective death of megakaryocyte progenitors and can be rescued by stem cell factor.

Current practice and future directions for optimization of platelet transfusions in patients with severe therapy-induced cytopenia.

BCL2/BCL-X(L) inhibition induces apoptosis, disrupts cellular calcium homeostasis, and prevents platelet activation.

Therapeutic platelet transfusion versus routine prophylactic transfusion in patients with haematological malignancies: an open-label, multicentre, randomised study.

A no-prophylaxis platelet-transfusion strategy for hematologic cancers.

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1557-1567

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scholarly article

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10.3324/HAEMATOL.2017.185165

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English

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103

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Paola E J van der Meijden

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2018-06-07T00:00:00Z

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29880611

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P932

6119160

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