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Phase transitions in the multi-cellular regulatory behavior of pancreatic islet excitabilityDeletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretionRapid and inexpensive fabrication of polymeric microfluidic devices via toner transfer maskingQuantitative 3D mapping of fluidic temperatures within microchannel networks using fluorescence lifetime imaging.Multi-photon excitation imaging of dynamic processes in living cells and tissues.Single-photon-counting detector for increased sensitivity in two-photon laser scanning microscopyThe MafA transcription factor becomes essential to islet β-cells soon after birth.Structurally distinct membrane nanotubes between human macrophages support long-distance vesicular traffic or surfing of bacteria.Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertensionA common polymorphism in extracellular superoxide dismutase affects cardiopulmonary disease risk by altering protein distribution.Fluorescence linear dichroism imaging for quantifying membrane orderTime-domain fluorescence lifetime imaging applied to biological tissue.Low Level Pro-inflammatory Cytokines Decrease Connexin36 Gap Junction Coupling in Mouse and Human Islets through Nitric Oxide-mediated Protein Kinase Cδ.Optical lock-in detection of FRET using synthetic and genetically encoded optical switches.Decreasing cx36 gap junction coupling compensates for overactive KATP channels to restore insulin secretion and prevent hyperglycemia in a mouse model of neonatal diabetes.New insights into the role of connexins in pancreatic islet function and diabetes.Cellular communication and heterogeneity in pancreatic islet insulin secretion dynamics.Dimensionality and size scaling of coordinated Ca(2+) dynamics in MIN6 β-cell clusters.Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans.Intrinsic islet heterogeneity and gap junction coupling determine spatiotemporal Ca²⁺ wave dynamicsA mathematical model of β-cells in an islet of Langerhans sensing a glucose gradient.Gap junctions and other mechanisms of cell-cell communication regulate basal insulin secretion in the pancreatic islet.Live cell linear dichroism imaging reveals extensive membrane ruffling within the docking structure of natural killer cell immune synapses.Time-resolved fluorescence imaging of solvent interactions in microfluidic devices.Age-Dependent Decline in the Coordinated [Ca2+] and Insulin Secretory Dynamics in Human Pancreatic Islets.New Understanding of β-Cell Heterogeneity and In Situ Islet Function.Exendin-4 Overcomes Cytokine-Induced Decreases in Gap Junction Coupling via PKA and Epac2 in Mouse and Human IsletsFluorescence-lifetime imaging of DNA-dye interactions within continuous-flow microfluidic systemsTwo-photon excitation microscopy for the study of living cells and tissuesContrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis in mouse models of type1 diabetes
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description
researcher ORCID ID = 0000-0002-5063-6096
@en
wetenschapper
@nl
name
Richard Benninger
@ast
Richard Benninger
@en
Richard Benninger
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Richard Benninger
@nl
type
label
Richard Benninger
@ast
Richard Benninger
@en
Richard Benninger
@es
Richard Benninger
@nl
prefLabel
Richard Benninger
@ast
Richard Benninger
@en
Richard Benninger
@es
Richard Benninger
@nl
P106
P31
P496
0000-0002-5063-6096