about
Sequential and selective Buchwald-Hartwig amination reactions for the controlled functionalization of 6-bromo-2-chloroquinoline: synthesis of ligands for the Tec Src homology 3 domain.Synthesis of N-benzylated-2-aminoquinolines as ligands for the Tec SH3 domain.Synthesis of 5-, 6- and 7-substituted-2-aminoquinolines as SH3 domain ligands.Identification and specificity studies of small-molecule ligands for SH3 protein domains.Enantioselective assay for the determination of perhexiline enantiomers in human plasma by liquid chromatography.Antimicrobial compounds from the Australian desert plant Eremophila neglecta.Aldehyde-sequestering drugs: tools for studying protein damage by lipid peroxidation products.In vitro antiviral activity of the anthraquinone chrysophanic acid against poliovirus.Mechanistic investigations on the reaction between 1,2-dioxines and bulky stabilized phosphorus ylides: an efficient route to closely related cyclopropane stereoisomers.Reactivity with Tris(hydroxymethyl)aminomethane confounds immunodetection of acrolein-adducted proteins.Protein adduct-trapping by hydrazinophthalazine drugs: mechanisms of cytoprotection against acrolein-mediated toxicity.Differences in lysine adduction by acrolein and methyl vinyl ketone: implications for cytotoxicity in cultured hepatocytes.Antiviral flavonoid from Pterocaulon sphacelatum, an Australian Aboriginal medicine.Antimicrobial compounds from Eremophila serrulataIn Vivo Activity of Benzoyl Ester Clerodane Diterpenoid Derivatives fromDodonaea polyandraMichael addition of acrolein to lysinyl and N-terminal residues of a model peptide: targets for cytoprotective hydrazino drugs
P50
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P50
description
researcher ORCID ID = 0000-0002-0061-5115
@en
wetenschapper
@nl
name
Simon M Pyke
@ast
Simon M Pyke
@en
Simon M Pyke
@es
Simon M Pyke
@nl
type
label
Simon M Pyke
@ast
Simon M Pyke
@en
Simon M Pyke
@es
Simon M Pyke
@nl
prefLabel
Simon M Pyke
@ast
Simon M Pyke
@en
Simon M Pyke
@es
Simon M Pyke
@nl
P1153
7005589537
P31
P496
0000-0002-0061-5115