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Role of HLA Adaptation in HIV EvolutionAnalysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing propertiesStructure and Interactions of the Human Programmed Cell Death 1 ReceptorPD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progressionRNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events.Additive contribution of HLA class I alleles in the immune control of HIV-1 infection.HLA-Cw*03-restricted CD8+ T-cell responses targeting the HIV-1 gag major homology region drive virus immune escape and fitness constraints compensated for by intracodon variationProgrammed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load.The hypervariable HIV-1 capsid protein residues comprise HLA-driven CD8+ T-cell escape mutations and covarying HLA-independent polymorphisms.Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR SelectionCD8+ TCR Bias and Immunodominance in HIV-1 Infection.Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection.Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point.HIV control through a single nucleotide on the HLA-B locus.Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection.Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virusCentral role of reverting mutations in HLA associations with human immunodeficiency virus set point.HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clusteringHLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients.Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection.Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study.Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy.Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection.Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression.Correction for Thobakgale et al., Impact of HLA in Mother and Child on Disease Progression of Pediatric Human Immunodeficiency Virus Type 1 Infection.Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling.Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopesDominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release.HIV control through a single nucleotide on the HLA-I locus.Biological differences between the sexes and susceptibility to tuberculosis.Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype.HLA Footprints on Human Immunodeficiency Virus Type 1 Are Associated with Interclade Polymorphisms and Intraclade Phylogenetic ClusteringCompensatory Mutation Partially Restores Fitness and Delays Reversion of Escape Mutation within the Immunodominant HLA-B*5703-Restricted Gag Epitope in Chronic Human Immunodeficiency Virus Type 1 InfectionCD8+ T-cell responses to different HIV proteins have discordant associations with viral loadHigh-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults
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description
Forscher
@de
chercheur
@fr
investigador
@es
researcher
@en
հետազոտող
@hy
研究者
@zh
name
Alasdair Leslie
@ast
Alasdair Leslie
@en
Alasdair Leslie
@es
Alasdair Leslie
@nl
type
label
Alasdair Leslie
@ast
Alasdair Leslie
@en
Alasdair Leslie
@es
Alasdair Leslie
@nl
prefLabel
Alasdair Leslie
@ast
Alasdair Leslie
@en
Alasdair Leslie
@es
Alasdair Leslie
@nl
P21
P31
P496
0000-0003-2538-6467