about
Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient miceA double-blind randomised controlled investigation into the efficacy of Mirococept (APT070) for preventing ischaemia reperfusion injury in the kidney allograft (EMPIRIKAL): study protocol for a randomised controlled trial.Strategies for targeting complement inhibitors in ischaemia/reperfusion injury.Recombinant complement receptor 2 radiolabeled with [99mTc(CO)3]+: a potential new radiopharmaceutical for imaging activated complementDeficiency of C5aR prolongs renal allograft survival.Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury.Intrarenal synthesis of complement.Role of the complement system in rejection.Toll-like receptors TLR2 and TLR4 initiate the innate immune response of the renal tubular epithelium to bacterial products.Role of complement in tubulointerstitial injury from proteinuria.Expression of complement components, receptors and regulators by human dendritic cells.Complement in organ transplantation.CD59a deficiency exacerbates ischemia-reperfusion injury in mice.The effect of locally synthesised complement on acute renal allograft rejection.Locally produced complement and its role in renal allograft rejection.Urinary tract infections: new insights into a common problem.Minireview: functions of the renal tract epithelium in coordinating the innate immune response to infection.Ultra-localization of Foxp3+ T cells within renal allografts shows infiltration of tubules mimicking rejection.Allograft rejection: effect of local synthesis of complement.Noninvasive Imaging of Activated Complement in Ischemia-Reperfusion Injury Post-Cardiac TransplantLate strut fracture in a Björk-Shiley valve prosthesis (current series).Mechanisms of disease: the complement system in renal injury--new ways of looking at an old foe.Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injuryThe relative importance of local and systemic complement production in ischaemia, transplantation and other pathologies.The complement factor 5a receptor 1 has a pathogenic role in chronic inflammation and renal fibrosis in a murine model of chronic pyelonephritisThe role of complement in regulating the alloresponse.Locally produced and activated complement as a mediator of alloreactive T cells.Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4.The role of complement in the early immune response to transplantation.Targeting complement at the time of transplantation.Mechanisms of rejection: role of complement.Control of innate immunological mechanisms as a route to drug minimization.Independent pathways of P-selectin and complement-mediated renal ischemia/reperfusion injury.Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.Role of the lectin complement pathway in kidney transplantation.CD46 (membrane cofactor protein) acts as a human epithelial cell receptor for internalization of opsonized uropathogenic Escherichia coli.Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.Predominant role for C5b-9 in renal ischemia/reperfusion injury.Molecular mapping of the HLA class II region in HLA-DR3 associated idiopathic membranous nephropathy.Rapid rejection of HLA-A2 transgenic skin graft due to indirect allorecognition.
P50
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P50
description
Forscher
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investigador
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հետազոտող
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Steven H Sacks
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Steven H Sacks
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Steven H Sacks
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Steven H Sacks
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Steven H Sacks
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Steven H Sacks
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Steven H Sacks
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Steven H Sacks
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Steven Sacks
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Steven H Sacks
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Steven H Sacks
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Steven H Sacks
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Steven H Sacks
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P108
P106
P108
P31
P496
0000-0001-6361-9095