about
Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteinsA novel RASA1 mutation causing capillary malformation-arteriovenous malformation (CM-AVM) presenting during pregnancyFunctional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertensionRegulation of bone morphogenetic protein signalling in human pulmonary vascular developmentMolecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasiaBMP4 induces HO-1 via a Smad-independent, p38MAPK-dependent pathway in pulmonary artery myocytesBone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cellsBMP9 mutations cause a vascular-anomaly syndrome with phenotypic overlap with hereditary hemorrhagic telangiectasiaPilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease.Targeting BMP signalling in cardiovascular disease and anaemiaMicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial HypertensionA Sex-Specific MicroRNA-96/5-Hydroxytryptamine 1B Axis Influences Development of Pulmonary HypertensionEndothelial apoptosis in pulmonary hypertension is controlled by a microRNA/programmed cell death 4/caspase-3 axisElabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial HypertensionBMPR2 mutations and survival in pulmonary arterial hypertension: an individual participant data meta-analysisBMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production.Adrenomedullin expression and growth inhibitory effects in distinct pulmonary artery smooth muscle cell subpopulations.Regulation and function of miR-214 in pulmonary arterial hypertension.MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension.A sex-specific reconstitution bias in the competitive CD45.1/CD45.2 congenic bone marrow transplant model.Future breakthroughs in the genetics of pulmonary arterial hypertension.MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblastsImatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study.Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia.Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline.Pulmonary arterial size and response to sildenafil in chronic thromboembolic pulmonary hypertension.Genetic and molecular mechanisms of pulmonary hypertension.Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension.A practical and efficient cellular substrate for the generation of induced pluripotent stem cells from adults: blood-derived endothelial progenitor cellsRegulation of bone morphogenetic protein 9 (BMP9) by redox-dependent proteolysis.Caveolae protect endothelial cells from membrane rupture during increased cardiac outputAn antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension.Long-term use of sildenafil in inoperable chronic thromboembolic pulmonary hypertension.Modulation of endothelin receptors in the failing right ventricle of the heart and vasculature of the lung in human pulmonary arterial hypertension.An official American Thoracic Society Statement: pulmonary hypertension phenotypesMolecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension.Transcript analysis reveals a specific HOX signature associated with positional identity of human endothelial cellsSex affects bone morphogenetic protein type II receptor signaling in pulmonary artery smooth muscle cells.Myocardin regulates vascular smooth muscle cell inflammatory activation and diseaseThe rise and rise of Pulmonary Circulation.
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description
researcher ORCID ID = 0000-0001-5700-9792
@en
wetenschapper
@nl
name
Nicholas W Morrell
@ast
Nicholas W Morrell
@en
Nicholas W Morrell
@nl
type
label
Nicholas W Morrell
@ast
Nicholas W Morrell
@en
Nicholas W Morrell
@nl
prefLabel
Nicholas W Morrell
@ast
Nicholas W Morrell
@en
Nicholas W Morrell
@nl
P214
P106
P21
P214
P31
P496
0000-0001-5700-9792
P735
P7859
lccn-nb2002022806