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Structure of the Tyrosine-sulfated C5a Receptor N Terminus in Complex with Chemotaxis Inhibitory Protein of Staphylococcus aureusActivity-based probes for rhomboid proteases discovered in a mass spectrometry-based assaySelective inhibition of the immunoproteasome by ligand-induced crosslinking of the active siteA proteinaceous fraction of wheat bran may interfere in the attachment of enterotoxigenic E. coli K88 (F4+) to porcine epithelial cellsUnusual binding of Grb2 protein to a bivalent polyproline-ligand immobilized on a SPR sensor: intermolecular bivalent binding.Influence of trifluoroethanol on membrane interfacial anchoring interactions of transmembrane alpha-helical peptides.Synthesis and structural investigations of N-alkylated beta-peptidosulfonamide-peptide hybrids of the amyloidogenic amylin(20-29) sequence: Implications of supramolecular folding for the design of peptide-based bionanomaterials.Rolling Loop Scan: An Approach Featuring Ring-Closing Metathesis for Generating Libraries of Peptides with Molecular Shapes Mimicking Bioactive Conformations or Local Folding of Peptides and Proteins.Discovery and in vivo evaluation of new melanocortin-4 receptor-selective peptides.Approaches to the solid phase of a cyclotriveratrylene scaffold-based tripodal library as potential artificial receptors.Synthesis of cyclic peptidosulfonamides as scaffolds for MC4 pharmacophoric groups.Binding of a diphosphorylated-ITAM peptide to spleen tyrosine kinase (Syk) induces distal conformational changes: a hydrogen exchange mass spectrometry study.Tilt angles of transmembrane model peptides in oriented and non-oriented lipid bilayers as determined by 2H solid-state NMR.A combinatorial approach toward smart libraries of discontinuous epitopes of HIV gp120 on a TAC synthetic scaffold.Scaffolded multiple cyclic peptide libraries for protein mimics by native chemical ligation.Computer-assisted molecular modeling of tumor promoters: rationale for the activity of phorbol esters, teleocidin B, and aplysiatoxin.Peptide transformation leading to peptide-peptidosulfonamide hybrids and oligo peptidosulfonamides.Backbone-modified amylin derivatives: implications for amyloid inhibitor design and as template for self-assembling bionanomaterials.Broad-spectrum antimalarial activity of peptido sulfonyl fluorides, a new class of proteasome inhibitors.Synthesis and applications of biomedical and pharmaceutical polymers via click chemistry methodologies.Strong inhibition of cholera toxin binding by galactose dendrimers.Synthesis of bicyclic alkene-/alkane-bridged nisin mimics by ring-closing metathesis and their biochemical evaluation as lipid II binders: toward the design of potential novel antibiotics.Inhibition of Streptococcus suis adhesion by dendritic galabiose compounds at low nanomolar concentration.Rigidified multivalent lactose molecules and their interactions with mammalian galectins: a route to selective inhibitors.Peptide Microarrays for Real-Time Kinetic Profiling of Tyrosine Phosphatase Activity of Recombinant Phosphatases and Phosphatases in Lysates of Cells or Tissue Samples.Cell permeable ITAM constructs for the modulation of mediator release in mast cells.Synthesis of DOTA-conjugated multimeric [Tyr3]octreotide peptides via a combination of Cu(I)-catalyzed "click" cycloaddition and thio acid/sulfonyl azide "sulfo-click" amidation and their in vivo evaluation.Synthesis and evaluation of new thiodigalactoside-based chemical probes to label galectin-3.The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia.Synthesis and biological activity of N-terminal lipidated and/or fluorescently labeled conjugates of astressin as corticotropin releasing factor antagonists.Characterization of a phosphorylated peptide and peptoid and peptoid-peptide hybrids by mass spectrometry.Synthesis of nisin AB dicarba analogs using ring-closing metathesis: influence of sp(3) versus sp(2) hybridization of the α-carbon atom of residues dehydrobutyrine-2 and dehydroalanine-5 on the lipid II binding affinity.Glucocorticoid-loaded core-cross-linked polymeric micelles with tailorable release kinetics for targeted therapy of rheumatoid arthritis.Molecular construction of HIV-gp120 discontinuous epitope mimics by assembly of cyclic peptides on an orthogonal alkyne functionalized TAC-scaffold.A peptide mimic of the chemotaxis inhibitory protein of Staphylococcus aureus: towards the development of novel anti-inflammatory compounds.Thermodynamics of phosphotyrosine peptide-peptoid hybrids binding to the p56lck SH2 domain.Detection of pathogenic Streptococcus suis bacteria using magnetic glycoparticles.Preparation of novel alkylated arginine derivatives suitable for click-cycloaddition chemistry and their incorporation into pseudosubstrate- and bisubstrate-based kinase inhibitors.The filament-specific Rep1-1 repellent of the phytopathogen Ustilago maydis forms functional surface-active amyloid-like fibrils.ITAM-derived phosphopeptide-containing dendrimers as multivalent ligands for Syk tandem SH2 domain.
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description
researcher ORCID ID = 0000-0001-8897-8975
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wetenschapper
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name
Rob M.J. Liskamp
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Rob M.J. Liskamp
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Rob M.J. Liskamp
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Rob M.J. Liskamp
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type
label
Rob M.J. Liskamp
@ast
Rob M.J. Liskamp
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Rob M.J. Liskamp
@es
Rob M.J. Liskamp
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prefLabel
Rob M.J. Liskamp
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Rob M.J. Liskamp
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Rob M.J. Liskamp
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Rob M.J. Liskamp
@nl
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0000-0001-8897-8975