about
The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombinationHuman topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediatesRMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stabilityA Role for USP7 in DNA ReplicationBudding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage.Identification of protein complexes required for efficient sister chromatid cohesion.Elg1 forms an alternative RFC complex important for DNA replication and genome integritySuppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae.The N- and C-termini of Elg1 contribute to the maintenance of genome stability.Genetic dissection of parallel sister-chromatid cohesion pathways.A survey of essential gene function in the yeast cell division cycleSlx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks.Global mapping of the yeast genetic interaction network.The INO80 chromatin remodeling complex prevents polyploidy and maintains normal chromatin structure at centromeresRMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complexComparative chemogenomics to examine the mechanism of action of dna-targeted platinum-acridine anticancer agentsChemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cellsAssembly of Slx4 signaling complexes behind DNA replication forksFunctional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction mapIntegration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways.Diversity of eukaryotic DNA replication origins revealed by genome-wide analysis of chromatin structure.Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repairA conserved domain of Schizosaccharomyces pombe dfp1(+) is uniquely required for chromosome stability following alkylation damage during S phaseSlx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4BLM and RMI1 alleviate RPA inhibition of TopoIIIα decatenase activityA genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damageAnalysis of Replicating Yeast Chromosomes by DNA Combing.Mapping the cellular response to small molecules using chemogenomic fitness signatures.The origin recognition complex links replication, sister chromatid cohesion and transcriptional silencing in Saccharomyces cerevisiae.Quantitative analysis of fitness and genetic interactions in yeast on a genome scale.Putting genetic interactions in context through a global modular decompositionRegulation of the replication initiator protein p65cdc18 by CDK phosphorylationLeveraging DNA damage response signaling to identify yeast genes controlling genome stability.Cdc7 kinases (DDKs) and checkpoint responses: lessons from two yeasts.A high-throughput confocal fluorescence microscopy platform to study DNA replication stress in yeast cells.Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotypeDampening DNA damage checkpoint signalling via coordinated BRCT domain interactions.Purification and characterization of DNA ligase I from the trypanosomatid Crithidia fasciculataGenetic Regulation of Dna2 Localization During the DNA Damage Response.
P50
Q24306030-924EDC16-77F7-4627-971A-8FCC1086D658Q24310243-E7600FBC-D42C-4AC9-844E-B150F358B347Q24544999-B1B2665A-D2E3-45F7-9DD4-59B6E99C687EQ24650860-56CA03EB-D06E-417A-A770-96B7B078244EQ27680523-61BE2FC7-8A0A-4715-ACCF-0E6E15DF04C0Q27930463-C7037033-8D00-4552-873A-99FF7D410837Q27931376-9D4B9BF6-70B9-4026-947D-7480575BE11BQ27931451-9A6C3810-2147-4FD3-B410-CD8E121C73AEQ27931827-4E7AB781-62EB-48FA-9077-ECFF4B0E2553Q27932360-20E02DFB-71E2-4F72-A376-DC20F4147D74Q27932555-C71B88DC-93DB-496C-BDCD-8712D2A47672Q27933676-BAB39927-C744-4258-B4B1-ABAC9529741CQ27934090-F41A9830-CB46-4AEA-9B90-BBB331292C94Q27934987-9F71650D-4585-43A4-9162-447890064C01Q27937243-24B92169-7A73-44EB-8F92-000C056FD057Q27939442-017A4FD8-AB07-4264-B1D0-17ECA66BF2FBQ28273778-33F1BB46-098D-4D92-9772-0ABCFB8C2D17Q28474096-6138B722-1809-4815-9B2E-C94893E0E998Q28608151-9D8EDD31-CCF8-42A9-BCA0-AEBBF984B80EQ29618911-FEF30A4F-A2A9-400E-AB7A-DF7D8F64A6BDQ30885679-6B0DD1C6-9D92-4FB9-9BB2-F3B5CDBBE2F9Q33686941-C2D0B83E-2E7F-45B3-BBC2-194F785C101AQ34115459-16A77B49-7F0B-48FE-BF55-4A1BFAC31A1FQ34283209-622D171D-7CED-4D12-B81C-E80AE2FC555BQ34298450-44AE1860-0CA2-4AED-9CF5-E7DC84C82806Q34387733-F27CBC0B-3522-4A24-8450-697FB44FB39CQ34430366-874FCB2D-2998-4B45-81C4-26BDABD45B03Q34511786-49319E83-2089-412D-A415-53BA3393E0EBQ34626429-6B993538-6D72-46AF-BBCF-FAB49686DF79Q34645049-65E2E6C1-F578-416B-8B1A-5CAA661ACF66Q35051808-EAF61B17-529D-4FC4-8E48-AA945BCC93D5Q35145534-8C24ADED-6EBB-46DD-9B04-DBF4CECDB57EQ35195434-E747A987-32B2-4291-976B-DEF7AE35B060Q35590051-721C61EB-4795-4B45-8186-989A6EA5FBD5Q35595515-4B6A216A-79F2-4544-A53D-353FD35244ACQ35615844-C16E2424-11C0-4332-B363-BDE1096222B4Q35760007-1EDD43B7-CC79-4BE9-84C3-6D4449FAF064Q35762655-0FA128C8-57EB-4324-9275-2673333420D7Q35923744-1CBD7C8F-36EB-452A-B35E-D7389347898EQ36012725-91853429-4F89-4A19-A90D-56DCEB02897D
P50
description
onderzoeker
@nl
researcher
@en
ricercatore
@it
հետազոտող
@hy
name
Grant W Brown
@ast
Grant W Brown
@en
Grant W Brown
@es
Grant W Brown
@nl
type
label
Grant W Brown
@ast
Grant W Brown
@en
Grant W Brown
@es
Grant W Brown
@nl
altLabel
Grant Brown
@en
prefLabel
Grant W Brown
@ast
Grant W Brown
@en
Grant W Brown
@es
Grant W Brown
@nl
P214
P106
P1153
35579896600
P21
P214
P31
P496
0000-0002-9002-5003
P734
P7859
lccn-n2015027098