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An Initial Event in the Insect Innate Immune Response: Structural and Biological Studies of Interactions between β-1,3-Glucan and the N-Terminal Domain of β-1,3-Glucan Recognition ProteinGet5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 ComplexTotal Synthesis and Characterization of 7-Hypoquinuclidonium Tetrafluoroborate and 7-Hypoquinuclidone BF3 ComplexEvaluation of NMR diffusion measurements for the conformational analysis of flexible peptides.Protonation of crotonyl-CoA dienolate by human glutaryl-CoA dehydrogenase occurs by solvent-derived protons.Preparation and physicochemical characterization of a novel water-soluble prodrug of carbamazepine.Total synthesis and evaluation of C26-hydroxyepothilone D derivatives for photoaffinity labeling of beta-tubulin.Kinetics and products of the acid-catalyzed ring-opening of atmospherically relevant butyl epoxy alcohols.A tandem Prins/Schmidt reaction approach to marine alkaloids: formal and total syntheses of lepadiformines A and CExperimental and theoretical investigations into the unusual regioselectivity of 4,5-, 5,6-, and 6,7-indole aryne cycloadditionsRegioselective Diels-Alder cycloadditions and other reactions of 4,5-, 5,6-, and 6,7-indole arynes.Biofilm-specific extracellular matrix proteins of nontypeable Haemophilus influenzaeHydrolysis of the prodrug, 2',3',5'-triacetyl-6-azauridine.Total synthesis and evaluation of C25-benzyloxyepothilone C for tubulin assembly and cytotoxicity against MCF-7 breast cancer cells.Comprehensive study of sansalvamide A derivatives and their structure-activity relationships against drug-resistant colon cancer cell lines.Site-specifically traced drug release and biodistribution of a paclitaxel-antibody conjugate toward improvement of the linker structure.Fibrolase. A fibrinolytic protein from snake venom.Two-, three-, and four-dimensional nuclear magnetic resonance spectroscopy of protein pharmaceuticals.Reactivity toward deamidation of asparagine residues in beta-turn structures.Characterization and dynamics of substituted ruthenacyclobutanes relevant to the olefin cross-metathesis reactionEffect of progressive benzyl substitution on the conformations of aminocaproic acid-cyclized dipeptides.Novel d-seco paclitaxel analogues: synthesis, biological evaluation, and model testing.Transport characteristics of peptides and peptidomimetics: II. Hydroxyethylamine bioisostere-containing peptidomimetics as substrates for the oligopeptide transporter and P-glycoprotein in the intestinal mucosa.Alternate substrates of human glutaryl-CoA dehydrogenase: structure and reactivity of substrates, and identification of a novel 2-enoyl-CoA product.Synthesis and conformational analysis of a coumarinic acid-based cyclic prodrug of an opioid peptide with modified sensitivity to esterase-catalyzed bioconversion.Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides.The effect of conformation on the membrane permeation of coumarinic acid- and phenylpropionic acid-based cyclic prodrugs of opioid peptides.New polyamide cryptand for anion binding.Hydrocotylosides I-VII, new oleanane saponins from hydrocotylesibthorpioides.Secondary structure of a dynamic type I'beta-hairpin peptide.Fluoride-facilitated deuterium exchange from DMSO-d6 to polyamide-based cryptands.Highly regioirregular polypropylene from asymmetric group 4 anilide(pyridine)phenoxide complexes.Lewis acid promoted titanium alkylidene formation: off-cycle intermediates relevant to olefin trimerization catalysis.Solution behavior of a novel type 1 interferon, interferon-tau.Conformation of ATP and ADP bound to N10-formyltetrahydrofolate synthetase determined by TRNOE NMR spectroscopy.The oxetane conformational lock of paclitaxel: structural analysis of D-secopaclitaxel.Modulating the Folding Landscape of Superoxide Dismutase 1 with Targeted Molecular Binders.Paclitaxel Analogues fromTaxus×mediacv. HicksiiConformational studies on resiniferatoxin (RTX), an ultrapotent vanilloid agonistEffect of zinc binding on the structure and stability of fibrolase, a fibrinolytic protein from snake venom
P50
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P50
description
Forscher
@de
chercheur
@fr
investigador
@es
researcher
@en
ricercatore
@it
wetenschapper
@nl
研究者
@zh
name
D G Vander Velde
@ast
D G Vander Velde
@en
D G Vander Velde
@es
D G Vander Velde
@nl
type
label
D G Vander Velde
@ast
D G Vander Velde
@en
D G Vander Velde
@es
D G Vander Velde
@nl
prefLabel
D G Vander Velde
@ast
D G Vander Velde
@en
D G Vander Velde
@es
D G Vander Velde
@nl
P108
P108
P31
P496
0000-0002-2907-0366