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Plasticity of the histone H2A genes in a Brazilian and six Colombian strains of Trypanosoma cruzi.Characterising the KMP-11 and HSP-70 recombinant antigens' humoral immune response profile in chagasic patients.The wide expansion of hepatitis delta virus-like ribozymes throughout trypanosomatid genomes is linked to the spreading of L1Tc/ingi clade mobile elements.Expression of inhibitory receptors and polyfunctional responses of T cells are linked to the risk of congenital transmission of T. cruzi.Short-term follow-up of chagasic patients after benzonidazole treatment using multiple serological markers.DNA immunization with Trypanosoma cruzi HSP70 fused to the KMP11 protein elicits a cytotoxic and humoral immune response against the antigen and leads to protection.Chagasic patients are able to respond against a viral antigen from influenza virus.Altering the motility of Trypanosoma cruzi with rabbit polyclonal anti-peptide antibodies reduces infection to susceptible mammalian cells.Differential phenotypic and functional profiles of TcCA-2 -specific cytotoxic CD8+ T cells in the asymptomatic versus cardiac phase in Chagasic patients.Characterization of an immunodominant antigenic epitope from Trypanosoma cruzi as a biomarker of chronic Chagas' disease pathology.Biomarkers of therapeutic responses in chronic Chagas disease: state of the art and future perspectives.The Trypanosomatid Pr77-hallmark contains a downstream core promoter element essential for transcription activity of the Trypanosoma cruzi L1Tc retrotransposon.Promiscuous Recognition of a Trypanosoma cruzi CD8+ T Cell Epitope among HLA-A2, HLA-A24 and HLA-A1 Supertypes in Chagasic Patients.Multiprimer PCR system for differential identification of mycobacteria in clinical samples.Biological markers for evaluating therapeutic efficacy in Chagas disease, a systematic review.Genomic cartography and proposal of nomenclature for the repeated, interspersed elements of the Leishmania major SIDER2 family and identification of SIDER2-containing transcripts.Effect of secondary anchor amino acid substitutions on the immunogenic properties of an HLA-A*0201-restricted T cell epitope derived from the Trypanosoma cruzi KMP-11 protein.Trypanosoma cruzi genotyping supports a common source of infection in a school-related oral outbreak of acute Chagas disease in Venezuela.Dataset for distribution of SIDER2 elements in the Leishmania major genome and transcriptome.A 12-mer repetitive antigenic epitope from Trypanosoma cruzi is a potential marker of therapeutic efficacy in chronic Chagas' disease.The innate immune response status correlates with a divergent clinical course in congenital Chagas disease of twins born in a non-endemic country.Risk factors and primary prevention of congenital Chagas disease in a nonendemic country.Trypanosoma cruzi paraflagellar rod proteins 2 and 3 contain immunodominant CD8(+) T-cell epitopes that are recognized by cytotoxic T cells from Chagas disease patients.Identification of a type I nitroreductase gene in non-virulent Trypanosoma rangeli.Antiparasitic Treatment Induces an Improved CD8+ T Cell Response in Chronic Chagasic Patients.Inhibitory Receptor Expression on CD8+ T Cells Is Linked to Functional Responses against Trypanosoma cruzi Antigens in Chronic Chagasic Patients.Identification of a Trypanosoma cruzi antigenic epitope implicated in the infectivity of fibroblast LLC-MK2 cells.A putative Leishmania DNA polymerase theta protects the parasite against oxidative damage.The L1Tc C-terminal domain from Trypanosoma cruzi non-long terminal repeat retrotransposon codes for a protein that bears two C2H2 zinc finger motifs and is endowed with nucleic acid chaperone activity.The L1Tc non-LTR retrotransposon of Trypanosoma cruzi contains an internal RNA-pol II-dependent promoter that strongly activates gene transcription and generates unspliced transcripts.Performance of Leishmania PFR1 recombinant antigen in serological diagnosis of asymptomatic canine leishmaniosis by ELISAMolecular characterization of the short interspersed repetitive element SIRE in the six discrete typing units (DTUs) of Trypanosoma cruzi.Characterization of SPf(66)n: a chimeric molecule used as a malaria vaccine.The non-LTR (long terminal repeat) retrotransposon L1Tc from Trypanosoma cruzi codes for a protein with RNase H activity.The endonuclease NL1Tc encoded by the LINE L1Tc from Trypanosoma cruzi protects parasites from daunorubicin DNA damage.Molecular characterization of the histone H2A gene from the parasite Trypanosoma rangeli.Molecular and immunological characterization of L14 ribosomal protein from Leishmania braziliensis.The effect of temperature on the stability of the synthetic SPf(66)n malaria vaccine.Cloning and molecular characterization of the cDNA encoding histone H1 from Leishmania braziliensis.Identification of HLA-A∗02:01-restricted CTL epitopes in Trypanosoma cruzi heat shock protein-70 recognized by Chagas disease patients.
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P50
description
researcher
@en
wetenschapper
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name
M C Thomas
@en
M C Thomas
@nl
type
label
M C Thomas
@en
M C Thomas
@nl
prefLabel
M C Thomas
@en
M C Thomas
@nl
P106
P31
P496
0000-0003-3586-9657