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Humanized theta-defensins (retrocyclins) enhance macrophage performance and protect mice from experimental anthrax infectionsImmunization of mice with formalin-inactivated spores from avirulent Bacillus cereus strains provides significant protection from challenge with Bacillus anthracis AmesHaemophilus ducreyi produces a novel sialyltransferase. Identification of the sialyltransferase gene and construction of mutants deficient in the production of the sialic acid-containing glycoform of the lipooligosaccharide.Cutting edge: resistance to Bacillus anthracis infection mediated by a lethal toxin sensitive allele of Nalp1b/Nlrp1b.Identification of small-molecule inhibitors of Yersinia pestis Type III secretion system YscN ATPase.Localization and assembly of proteins comprising the outer structures of the Bacillus anthracis spore.A Yersinia pestis tat mutant is attenuated in bubonic and small-aerosol pneumonic challenge models of infection but not as attenuated by intranasal challengeExposure to Bacillus anthracis capsule results in suppression of human monocyte-derived dendritic cellsCharacterization of tetratricopeptide repeat-like proteins in Francisella tularensis and identification of a novel locus required for virulenceInterrogation of the Burkholderia pseudomallei genome to address differential virulence among isolates.Characterization of Burkholderia pseudomallei Strains Using a Murine Intraperitoneal Infection Model and In Vitro Macrophage Assays.Two stable variants of Burkholderia pseudomallei strain MSHR5848 express broadly divergent in vitro phenotypes associated with their virulence differences.Characterization of pathogenesis of and immune response to Burkholderia pseudomallei K96243 using both inhalational and intraperitoneal infection models in BALB/c and C57BL/6 mice.A spontaneous mutation in kdsD, a biosynthesis gene for 3 Deoxy-D-manno-Octulosonic Acid, occurred in a ciprofloxacin resistant strain of Francisella tularensis and caused a high level of attenuation in murine models of tularemia.Disrupting the luxS quorum sensing gene does not significantly affect Bacillus anthracis virulence in mice or guinea pigs.Phenotypic Characterization of a Novel Virulence-Factor Deletion Strain of Burkholderia mallei That Provides Partial Protection against Inhalational Glanders in MiceRoles of the Bacillus anthracis spore protein ExsK in exosporium maturation and germination.Key aspects of the molecular and cellular basis of inhalational anthrax.Animal Models for the Pathogenesis, Treatment, and Prevention of Infection by Bacillus anthracis.The Bacillus anthracis Exosporium: What's the Big "Hairy" Deal?The role of the phoPQ operon in the pathogenesis of the fully virulent CO92 strain of Yersinia pestis and the IP32953 strain of Yersinia pseudotuberculosis.The impact of inducing germination of Bacillus anthracis and Bacillus thuringiensis spores on potential secondary decontamination strategies.D-cycloserine or similar physiochemical compounds may be uniquely suited for use in Bacillus anthracis spore decontamination strategies.Analysis of a novel spore antigen in Bacillus anthracis that contributes to spore opsonization.An unusual inhalational exposure to Bacillus anthracis in a research laboratory.The NheA component of the non-hemolytic enterotoxin of Bacillus cereus is produced by Bacillus anthracis but is not required for virulence.Effects of altering the germination potential of Bacillus anthracis spores by exogenous means in a mouse model.Facile construction of mutations in Haemophilus ducreyi using lacZ as a counter-selectable marker.A Standard Method to Inactivate Bacillus anthracis Spores to Sterility Using γ-Irradiation.A Yersinia pestis YscN ATPase mutant functions as a live attenuated vaccine against bubonic plague in mice
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description
researcher
@en
wetenschapper
@nl
name
J A Bozue
@en
J A Bozue
@nl
type
label
J A Bozue
@en
J A Bozue
@nl
prefLabel
J A Bozue
@en
J A Bozue
@nl
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P31
P496
0000-0001-6959-8176