about
The liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E4-(3-Aryloxyaryl)quinoline sulfones are potent liver X receptor agonistsDiscovery of a new binding mode for a series of liver X receptor agonistsDiscovery and structure-guided optimization of tert-butyl 6-(phenoxymethyl)-3-(trifluoromethyl)benzoates as liver X receptor agonistsInhibition of tumor growth and progression of LNCaP prostate cancer cells in athymic mice by androgen and liver X receptor agonistAntiproliferative effect of liver X receptor agonists on LNCaP human prostate cancer cellsLiver X Receptor Agonist TO901317 Attenuates Paraquat-Induced Acute Lung Injury through Inhibition of NF-κB and JNK/p38 MAPK Signal Pathways.Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling.ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice.Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines.Effects of the synthetic liver X receptor agonist T0901317 on the growth hormone and thyroid hormone axes in male rats.Liver X receptor agonist inhibits proliferation of ovarian carcinoma cells stimulated by oxidized low density lipoprotein.ICAM-1-Targeted Liposomes Loaded with Liver X Receptor Agonists Suppress PDGF-Induced Proliferation of Vascular Smooth Muscle Cells.Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice.Liver X receptor agonist treatment attenuates cardiac dysfunction in type 2 diabetic db/db mice.Low dose of the liver X receptor agonist, AZ876, reduces atherosclerosis in APOE*3Leiden mice without affecting liver or plasma triglyceride levels.A novel potent synthetic steroidal liver X receptor agonist lowers plasma cholesterol and triglycerides and reduces atherosclerosis in LDLR(-/-) miceLiver X receptor agonists as potential therapeutic agents for dyslipidemia and atherosclerosis.Targeted disruption of the idol gene alters cellular regulation of the low-density lipoprotein receptor by sterols and liver x receptor agonists.Nanoparticles containing a liver X receptor agonist inhibit inflammation and atherosclerosisRetinoic acid and liver X receptor agonist synergistically inhibit HIV infection in CD4+ T cells by up-regulating ABCA1-mediated cholesterol efflux.Regulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists.Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient miceTreatment with TO901317, a synthetic liver X receptor agonist, reduces brain damage and attenuates neuroinflammation in experimental intracerebral hemorrhage.Effects of liver X receptor agonist treatment on pulmonary inflammation and host defense.Liver X receptor agonist modulation of cholesterol efflux in mice with intestine-specific deletion of microsomal triglyceride transfer proteinAntiatherosclerotic effects of a novel synthetic tissue-selective steroidal liver X receptor agonist in low-density lipoprotein receptor-deficient mice.Dissociated sterol-based liver X receptor agonists as therapeutics for chronic inflammatory diseases.The liver X receptor agonist TO901317 protects mice against cisplatin-induced kidney injury.Differential anti-atherosclerotic effects in the innominate artery and aortic sinus by the liver X receptor agonist T0901317The liver X receptor agonist T0901317 acts as androgen receptor antagonist in human prostate cancer cells.Liver X receptor agonist regulation of Th17 lymphocyte function in autoimmunityLiver X receptor agonist T0901317 reverses resistance of A549 human lung cancer cells to EGFR-TKI treatment.Liver X receptor agonist T0901317 reduces atherosclerotic lesions in apoE-/- mice by up-regulating NPC1 expression.Liver X receptor agonists inhibit tissue factor expression in macrophages.Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels.
P921
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P921
description
class of chemical compounds with an agonist activity against the liver X receptor
@en
name
liver X receptor agonist
@en
type
label
liver X receptor agonist
@en
prefLabel
liver X receptor agonist
@en