about
The First-in-class Anti-EGFR Antibody Mixture Sym004 Overcomes Cetuximab Resistance Mediated by EGFR Extracellular Domain Mutations in Colorectal Cancer.Long-term Coexposure to Hexavalent Chromium and B[a]P Causes Tissue-Specific Differential Biological Effects in Liver and Gastrointestinal Tract of MicePrenatal and early postnatal lead exposure in mice: neuroimaging findingsLead induces similar gene expression changes in brains of gestationally exposed adult mice and in neurons differentiated from mouse embryonic stem cells.Sex- and tissue-specific methylome changes in brains of mice perinatally exposed to lead.AhR-dependent 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in human neuronal cell line SHSY5Y.2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptosis by disruption of intracellular calcium homeostasis in human neuronal cell line SHSY5Y.NMDA-induced neuroprotection in hippocampal neurons is mediated through the protein kinase A and CREB (cAMP-response element-binding protein) pathway.Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNA Analyses: A Phase 2 Randomized Clinical Trial.Chromium disrupts chromatin organization and CTCF access to its cognate sites in promoters of differentially expressed genes.
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description
investigador
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researcher
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wetenschapper
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name
Francisco J Sánchez-Martín
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Francisco J Sánchez-Martín
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type
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Francisco J Sánchez-Martín
@en
Francisco J Sánchez-Martín
@nl
prefLabel
Francisco J Sánchez-Martín
@en
Francisco J Sánchez-Martín
@nl
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P31
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0000-0002-9599-4380