about
Translation initiation factor eIF3 promotes programmed stop codon readthrough.Translation initiation factors eIF3 and HCR1 control translation termination and stop codon read-through in yeast cellsFunctional and biochemical characterization of human eukaryotic translation initiation factor 3 in living cells.The indispensable N-terminal half of eIF3j/HCR1 cooperates with its structurally conserved binding partner eIF3b/PRT1-RRM and with eIF1A in stringent AUG selectionThe C-terminal region of eukaryotic translation initiation factor 3a (eIF3a) promotes mRNA recruitment, scanning, and, together with eIF3j and the eIF3b RNA recognition motif, selection of AUG start codons.Reporters transiently transfected into mammalian cells are highly sensitive to translational repression induced by dsRNA expression.Functional characterization of the role of the N-terminal domain of the c/Nip1 subunit of eukaryotic initiation factor 3 (eIF3) in AUG recognition.Human eIF3b and eIF3a serve as the nucleation core for the assembly of eIF3 into two interconnected modules: the yeast-like core and the octamer.Embraced by eIF3: structural and functional insights into the roles of eIF3 across the translation cycle.Does eIF3 promote reinitiation after translation of short upstream ORFs also in mammalian cells?uS3/Rps3 controls fidelity of translation termination and programmed stop codon readthrough in co-operation with eIF3
P50
Q27937003-B654FAF6-0EAE-4BF3-A662-9D893CF9F6E5Q28535333-E9D2A93F-4B15-417E-BFA7-61E631B13645Q34056518-22ED6257-9282-4E1A-A605-BAFDBE87954FQ34091806-5212EDFC-972E-496C-A511-FD0C56F3CF7CQ34119657-0ECDB76F-A7D7-4BBB-9C24-3F390B7F6114Q37521220-35321CE5-70EC-448B-A47C-EF68FD1C71D7Q41974670-2C23F1A6-ACAE-492A-ABFB-458B904731C0Q42351633-2EB1DAFC-7D58-42FD-A62F-3E2D5CD9C99DQ47234689-176D1B4E-966E-49FA-98E1-1CC4A22596F4Q48025687-002239C4-38D8-412C-B4D7-4DD9E4AA37F4Q90898963-47FAA3C3-C0FF-4810-B47B-18BDB8082559
P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Susan Wagner
@en
Susan Wagner
@nl
type
label
Susan Wagner
@en
Susan Wagner
@nl
prefLabel
Susan Wagner
@en
Susan Wagner
@nl
P31
P496
0000-0002-7492-7541