Netrin-UNC5B signaling Pathway - sprookjes - yvandenbroek - TriplyDB

Netrin-UNC5B signaling Pathway

Netrin-UNC5B signaling Pathway

http://www.wikidata.org/entity/Q84971596

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Netrin-UNC5B signaling Pathway

http://www.wikidata.org/entity/Q84971596

description

UNC-5 Homolog B (UNC5B) is a m ...... posing processes. UNC5B sig...

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name

Netrin-UNC5B signaling Pathway

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type

label

Netrin-UNC5B signaling Pathway

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prefLabel

Netrin-UNC5B signaling Pathway

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Netrin-UNC5B signaling Pathway

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P2093

Denise Slenter

http://www.w3.org/2001/XMLSchema#string

Friederike Ehrhart

http://www.w3.org/2001/XMLSchema#string

Lauren J. Dupuis

http://www.w3.org/2001/XMLSchema#string

Marvin Martens

http://www.w3.org/2001/XMLSchema#string

Yashwanth Subbannayya

http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B

The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase

The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase

p53RDL1 regulates p53-dependent apoptosis

Tyrosine phosphorylation of netrin receptors in netrin-1 signaling

Netrin-3, a mouse homolog of human NTN2L, is highly expressed in sensory ganglia and shows differential binding to netrin receptors

Netrin-4 promotes mural cell adhesion and recruitment to endothelial cells.

Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B.

Interfering with multimerization of netrin-1 receptors triggers tumor cell death.

Netrin-1 acts as a survival factor via its receptors UNC5H and DCC.

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biological pathway

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Friederike Ehrhart

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