Bergmann azlactone peptide synthesis

The Bergmann azlactone peptide synthesis is a classic organic synthesis process for the preparation of dipeptides. In the presence of a base, peptides are formed. s of N-carboxyanhydrides of amino acids with amino acid esters . This reaction can be looked at in further detail by Bailey. The resulting peptide is then protected by esters of benzylchroroformate in order to keep the amino groups intact . This mechanism serves as a source of protection for the amino group in the amino acid. The ester will block the amino group from binding with other molecules.

Bergmann azlactone peptide synthesis

The Bergmann azlactone peptide synthesis is a classic organic synthesis process for the preparation of dipeptides. In the presence of a base, peptides are formed. s of N-carboxyanhydrides of amino acids with amino acid esters . This reaction can be looked at in further detail by Bailey. The resulting peptide is then protected by esters of benzylchroroformate in order to keep the amino groups intact . This mechanism serves as a source of protection for the amino group in the amino acid. The ester will block the amino group from binding with other molecules.