HSPA8
Heat shock 70 kDa protein 8 also known as heat shock cognate 71 kDa protein or Hsc70 or Hsp73 is a heat shock protein that in humans is encoded by the HSPA8 gene on chromosome 11. As a member of the heat shock protein 70 family and a chaperone protein, it facilitates the proper folding of newly translated and misfolded proteins, as well as stabilize or degrade mutant proteins. Its functions contribute to biological processes including signal transduction, apoptosis, autophagy, protein homeostasis, and cell growth and differentiation. It has been associated with an extensive number of cancers, neurodegenerative diseases, cell senescence, and aging.
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AutophagyBAG1BAG2BAG3BAG4CDC5LCITED1Chaperone-assisted selective autophagyDNAJA3DNAJC5GAK (protein)HSPA8 (gene)HSPBP1Heat shock proteinHepatitis EHousekeeping geneHsc70Hsc70 heat-shock proteinsHsp70Large tumor antigenList of MeSH codes (D12.776)List of human protein-coding genes 2Middle tumor antigenParkin (ligase)RicinSTUB1Small tumor antigenVPS35
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HSPA8
Heat shock 70 kDa protein 8 also known as heat shock cognate 71 kDa protein or Hsc70 or Hsp73 is a heat shock protein that in humans is encoded by the HSPA8 gene on chromosome 11. As a member of the heat shock protein 70 family and a chaperone protein, it facilitates the proper folding of newly translated and misfolded proteins, as well as stabilize or degrade mutant proteins. Its functions contribute to biological processes including signal transduction, apoptosis, autophagy, protein homeostasis, and cell growth and differentiation. It has been associated with an extensive number of cancers, neurodegenerative diseases, cell senescence, and aging.
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Heat shock 70 kDa protein 8 al ...... s, cell senescence, and aging.
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Heat shock 70 kDa protein 8 al ...... s, cell senescence, and aging.
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HSPA8
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