Immunoglobulin heavy chain
The immunoglobulin heavy chain (IgH) is the large polypeptide subunit of an antibody (immunoglobulin). In human genome, the IgH gene loci are on chromosome 14. A typical antibody is composed of two immunoglobulin (Ig) heavy chains and two Ig light chains. Several different types of heavy chain exist that define the class or isotype of an antibody. These heavy chain types vary between different animals. All heavy chains contain a series of immunoglobulin domains, usually with one variable domain (VH) that is important for binding antigen and several constant domains (CH1, CH2, etc.). Production of a viable heavy chain is a key step in B cell maturation. If the heavy chain is able to bind to a surrogate light chain and move to the plasma membrane, then the developing B cell can begin produci
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Acute lymphoblastic leukemiaAlirocumabAmyloidAntibodyAntibody heavy chainAvian immune systemBCL7AB cellBevacizumabBispecific monoclonal antibody1,2-dimethoxyethaanCatumaxomabChromosome 14Complementarity-determining regionConformational dynamics data bankDNA repair protein XRCC4Duodenal-type follicular lymphomaETV6Enhancer (genetics)Epstein–Barr virus-associated lymphoproliferative diseasesFCER1Fragment antigen-bindingFrederick AltGPR132Gerald EdelmanH-chainHeavy-chain antibodyHeavy chainHeavy chain diseaseHeavychain immunoglobulinHuman somatic variationHumoral immune deficiencyHyper IgM syndromeHypervariable regionID4IGHIGH@IgHImmunoglobulin DImmunoglobulin M
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Immunoglobulin heavy chain
The immunoglobulin heavy chain (IgH) is the large polypeptide subunit of an antibody (immunoglobulin). In human genome, the IgH gene loci are on chromosome 14. A typical antibody is composed of two immunoglobulin (Ig) heavy chains and two Ig light chains. Several different types of heavy chain exist that define the class or isotype of an antibody. These heavy chain types vary between different animals. All heavy chains contain a series of immunoglobulin domains, usually with one variable domain (VH) that is important for binding antigen and several constant domains (CH1, CH2, etc.). Production of a viable heavy chain is a key step in B cell maturation. If the heavy chain is able to bind to a surrogate light chain and move to the plasma membrane, then the developing B cell can begin produci
has abstract
A cadeia pesada das imunoglobu ...... eína de união à cadeia pesada.
@pt
En immunologia es denomina cad ...... ersos dominis constants (IgC).
@ca
En inmunología se denomina cad ...... ios dominios constantes (IgC).
@es
Rantai berat (en:heavy chain, ...... but kemudian dikenal sebagai .
@in
The immunoglobulin heavy chain ...... a heavy-chain binding protein.
@en
Тяжёлые цепи иммуноглобулинов ...... несколько константных доменов.
@ru
免疫グロブリン重鎖(めんえきグロブリンじゅうさ、英: imm ...... ができ、重鎖が重鎖結合タンパク質に結合することを可能にする。
@ja
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1,009,479,106
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A cadeia pesada das imunoglobu ...... a produzir a sua cadeia leve.
@pt
En immunologia es denomina cad ...... ersos dominis constants (IgC).
@ca
En inmunología se denomina cad ...... ios dominios constantes (IgC).
@es
Rantai berat (en:heavy chain, ...... ti (misalnya , kinesin atau ).
@in
The immunoglobulin heavy chain ...... oping B cell can begin produci
@en
Тяжёлые цепи иммуноглобулинов ...... несколько константных доменов.
@ru
免疫グロブリン重鎖(めんえきグロブリンじゅうさ、英: imm ...... ができ、重鎖が重鎖結合タンパク質に結合することを可能にする。
@ja
label
Cadeia pesada das imunoglobulinas
@pt
Cadena pesada
@es
Cadena pesant d'immunoglobulina
@ca
Immunoglobulin heavy chain
@en
Rantai berat
@in
Тяжёлые цепи иммуноглобулинов
@ru
免疫グロブリン重鎖
@ja