The siege of Malta, also known as the siege of Valletta or the French blockade (Maltese: L-Imblokk tal-Franċiżi), was a two-year siege and blockade of the French garrison in Valletta and the Three Cities, the largest settlements and main port on the Mediterranean island of Malta, between 1798 and 1800. Malta had been captured by a French expeditionary force during the Mediterranean campaign of 1798, and garrisoned with 3,000 men under the command of Claude-Henri Belgrand de Vaubois. After the British Royal Navy destroyed the French Mediterranean Fleet at the Battle of the Nile on 1 August 1798, the British were able to initiate a blockade of Malta, assisted by an uprising among the native Maltese population against French rule. After its retreat to Valletta, the French garrison faced sever