"Something Against You" is the seventh episode of the twelfth season of the American television medical drama Grey's Anatomy, and the 252nd episode overall. It aired November 12, 2015 on ABC in the United States. The episode was written by Andy Reaser and directed by Geary McLeod. On its initial airing the episode was watched by 8.02 million viewers and opened up to mixed reviews from television critics with praise going to the performance of Ellen Pompeo and Kevin McKidd and the focus brought on their characters while criticism was faced by the writers for the storylines in particular the arcs involving Sarah Drew and Jesse Williams's and Samantha Sloyan's characters.