Crosslinking of DNA
In genetics, crosslinking of DNA occurs when various exogenous or endogenous agents react with two nucleotides of DNA, forming a covalent linkage between them. This crosslink can occur within the same strand (intrastrand) or between opposite strands of double-stranded DNA (interstrand). These adducts interfere with cellular metabolism, such as DNA replication and transcription, triggering cell death. These crosslinks can, however, be repaired through excision or recombination pathways.
Agata SmogorzewskaAncient DNAAngelicinArchaeal transcription factor BArsenic biochemistryAzinomycin BBiogerontologyBusulfanCancer syndromeCarmustineChIP sequencingChromatin immunoprecipitationChromosome conformation captureColibactinCross-linkCynthia BurrowsDCLRE1BDNA crosslinkDNA crosslinkingDNA damage theory of agingDNA repairDNA repair-deficiency disorderDNA replication stressERCC6ERCC8 (gene)FAN1FANCAFANCGFANCLFanconi anemiaFree-radical theory of agingFurazolidoneGlossary of geneticsImmunoreceptor tyrosine-based inhibitory motifInterstrand crosslinksIntrastrand crosslinkJanuary–March 2020 in scienceMetalloenediynesMitomycin_CMitotic recombination
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Crosslinking of DNA
In genetics, crosslinking of DNA occurs when various exogenous or endogenous agents react with two nucleotides of DNA, forming a covalent linkage between them. This crosslink can occur within the same strand (intrastrand) or between opposite strands of double-stranded DNA (interstrand). These adducts interfere with cellular metabolism, such as DNA replication and transcription, triggering cell death. These crosslinks can, however, be repaired through excision or recombination pathways.
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Die DNA-Vernetzung bezeichnet ...... n, einer Form der DNA-Schäden.
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In genetics, crosslinking of D ...... ow proteins interact with DNA.
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Die DNA-Vernetzung bezeichnet ...... n, einer Form der DNA-Schäden.
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In genetics, crosslinking of D ...... ion or recombination pathways.
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Crosslinking of DNA
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DNA-Vernetzung
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