Homestead is an unincorporated community in Baker County, in the U.S. state of Oregon. Homestead lies on the Snake River south of Hells Canyon National Recreation Area and about 4 miles (6 km) north of Copperfield and Oxbow. The community was named for the homestead claim of Frank E. Pearce, who conducted operations at the nearby Iron Dyke Mine around 1900. J. H. Pearson was the first postmaster of the Homestead post office, which operated until May 1, 1965. The post office at Oxbow then replaced the office at Homestead.