National Route 5 (国道5号, Kokudō Go-gō) is a major highway on the island and prefecture of Hokkaido in northern Japan. The 288.5-kilometer (179.3 mi) highway begins at an intersection with National Routes 279 and 278 in Hakodate. It travels north across the southern half of the island, traveling through Otaru where it curves to the east toward its endpoint at an intersection with National Route 12 in Chūō-ku, Sapporo.