Morphiceptin
Morphiceptin is a tetrapeptide (Tyr-Pro-Phe-Pro-NH2) that is a selective μ-opioid receptor agonist. It is derived from β-casomorphin and has over 1,000 times selectivity for μ- over δ-opioid receptors. When injected intracerebroventricularly (into the ventricular system of the brain), morphiceptin had an analgesic ED50 of 1.7 nmol per animal. The analgesic effects of morphiceptin were reversed by naloxone, meaning that the analgesic effect is mediated by the μ-opioid receptor. Morphiceptin is the (1S,2S,3S,4S)-form whereas is the (1S,2S,3S,4R)-form [84799-23-5].
Wikipage redirect
Link from a Wikipage to another Wikipage
primaryTopic
Morphiceptin
Morphiceptin is a tetrapeptide (Tyr-Pro-Phe-Pro-NH2) that is a selective μ-opioid receptor agonist. It is derived from β-casomorphin and has over 1,000 times selectivity for μ- over δ-opioid receptors. When injected intracerebroventricularly (into the ventricular system of the brain), morphiceptin had an analgesic ED50 of 1.7 nmol per animal. The analgesic effects of morphiceptin were reversed by naloxone, meaning that the analgesic effect is mediated by the μ-opioid receptor. Morphiceptin is the (1S,2S,3S,4S)-form whereas is the (1S,2S,3S,4R)-form [84799-23-5].
has abstract
Morphiceptin is a tetrapeptide ...... S,2S,3S,4R)-form [84799-23-5].
@en
alternative name
Tyr-Pro-Phe-Pro-NH2, PLO17
@en
IUPAC name
(2S)-1-[(2S)-2-amino-3-(4-hydr ...... 2-yl]pyrrolidine-2-carboxamide
@en
Wikipage page ID
32,596,986
page length (characters) of wiki page
Wikipage revision ID
999,876,325
Link from a Wikipage to another Wikipage
ImageFile
@en
IUPACName
OtherNames
Tyr-Pro-Phe-Pro-NH2, PLO17
@en
Verifiedfields
changed
@en
verifiedrevid
442,867,817
Watchedfields
changed
@en
wikiPageUsesTemplate
subject
hypernym
comment
Morphiceptin is a tetrapeptide ...... S,2S,3S,4R)-form [84799-23-5].
@en
label
Morphiceptin
@en