Mutagenesis (molecular biology technique)
In molecular biology, mutagenesis is an important laboratory technique whereby DNA mutations are deliberately engineered to produce libraries of mutant genes, proteins, strains of bacteria, or other genetically modified organisms. The various constituents of a gene, as well as its regulatory elements and its gene products, may be mutated so that the functioning of a genetic locus, process, or product can be examined in detail. The mutation may produce mutant proteins with interesting properties or enhanced or novel functions that may be of commercial use. Mutant strains may also be produced that have practical application or allow the molecular basis of a particular cell function to be investigated.
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Affinity maturationAlanine scanningAsymmetric PCRCassette mutagenesisDeoxyribozymeDirected evolutionENUError-prone PCREsther LederbergEthyl methanesulfonateGenetic engineeringGenetic engineering techniquesGenetic saturationGlauco Tocchini-ValentiniIllegitimate recombinationLentilLibrary (biology)Margaret RobinsonMolecular geneticsMutagenesis (molecular biology)New Breeding TechniquesProtease-activated receptor 2Protein engineeringRandom mutagenesisRavi AlladaRibozymeSaturation mutagenesisSequence saturation mutagenesisSequence space (evolution)Site-directed mutagenesisThermostabilityVrille (gene)
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Mutagenesis (molecular biology technique)
In molecular biology, mutagenesis is an important laboratory technique whereby DNA mutations are deliberately engineered to produce libraries of mutant genes, proteins, strains of bacteria, or other genetically modified organisms. The various constituents of a gene, as well as its regulatory elements and its gene products, may be mutated so that the functioning of a genetic locus, process, or product can be examined in detail. The mutation may produce mutant proteins with interesting properties or enhanced or novel functions that may be of commercial use. Mutant strains may also be produced that have practical application or allow the molecular basis of a particular cell function to be investigated.
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In molecular biology, mutagene ...... ases such as beta thalassemia.
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Mutagenesis
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In molecular biology, mutagene ...... l function to be investigated.
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Mutagenesis (molecular biology technique)
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