Proprotein convertase
Proprotein convertases (PPCs) are a family of proteins that activate other proteins. Many proteins are inactive when they are first synthesized, because they contain chains of amino acids that block their activity. Proprotein convertases remove those chains and activate the protein. The prototypical proprotein convertase is furin. Proprotein convertases have medical significance, because they are involved in many important biological processes, such as cholesterol synthesis. Compounds called proprotein convertase inhibitors can block their action, and block the target proteins from becoming active. Many proprotein convertases, especially furin and PACE4, are involved in pathological processes such as viral infection, inflammation, hypercholesterolemia, and cancer, and have been postulated
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Beta-EndorphinCarboxypeptidase ECharles BrennerCorticotropic cellFurinGlucagon-like peptide-11,2-dimethoxyethaanInsulinKexinList of MeSH codes (D08)Low-density lipoproteinNabil SeidahNodal signaling pathwayPCSK5PCSK6PCSK9PMEL (gene)PcskProhormone convertaseProopiomelanocortinProperdinProprotein convertase 2Proprotein convertase 5Proprotein convertasesSecretory Pathway Ca²⁺ ATPaseSysteminVascular endothelial growth factor C
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Proprotein convertase
Proprotein convertases (PPCs) are a family of proteins that activate other proteins. Many proteins are inactive when they are first synthesized, because they contain chains of amino acids that block their activity. Proprotein convertases remove those chains and activate the protein. The prototypical proprotein convertase is furin. Proprotein convertases have medical significance, because they are involved in many important biological processes, such as cholesterol synthesis. Compounds called proprotein convertase inhibitors can block their action, and block the target proteins from becoming active. Many proprotein convertases, especially furin and PACE4, are involved in pathological processes such as viral infection, inflammation, hypercholesterolemia, and cancer, and have been postulated
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As pró-convertases são um dos ...... infecções e como o Alzheimer.
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Proprotein convertases (PPCs) ...... ts for some of these diseases.
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As pró-convertases são um dos ...... infecções e como o Alzheimer.
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Proprotein convertases (PPCs) ...... cer, and have been postulated
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Proprotein convertase
@en
Pró-convertase
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