Protein phosphatase 2
Protein phosphatase 2 (PP2), also known as PP2A, is an enzyme that in humans is encoded by the PPP2CA gene. The PP2A heterotrimeric protein phosphatase is ubiquitously expressed, accounting for a large fraction of phosphatase activity in eukaryotic cells. Its serine/threonine phosphatase activity has a broad substrate specificity and diverse cellular functions. Among the targets of PP2A are proteins of oncogenic signaling cascades, such as Raf, MEK, and AKT, where PP2A may act as a tumor suppressor.
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Protein phosphatase 2
Protein phosphatase 2 (PP2), also known as PP2A, is an enzyme that in humans is encoded by the PPP2CA gene. The PP2A heterotrimeric protein phosphatase is ubiquitously expressed, accounting for a large fraction of phosphatase activity in eukaryotic cells. Its serine/threonine phosphatase activity has a broad substrate specificity and diverse cellular functions. Among the targets of PP2A are proteins of oncogenic signaling cascades, such as Raf, MEK, and AKT, where PP2A may act as a tumor suppressor.
has abstract
La protéine phosphatase 2 (PP2 ...... es qui réduisent son activité.
@fr
Protein phosphatase 2 (PP2), a ...... may act as a tumor suppressor.
@en
Белок фосфатазы 2 (PP2) (англ. ...... каскадов, такие как , , и AKT.
@ru
プロテインホスファターゼ2 (protein phospha ...... のタンパク質が含まれ、PP2Aはがん抑制因子として機能する。
@ja
蛋白磷酸酶2（英語：Protein phosphatase ...... PP2A的底物都是信号传导级联反应中的癌蛋白，如AKT、和。
@zh
EC number
locus supplementary data
OMIM id
RefSeq
NM_001009552
Wikipage page ID
20,177,401
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Wikipage revision ID
1,006,468,116
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Arm
p
@en
q
@en
caption
The catalytic subunit of prot ...... upying the active site. From .
@en
ECnumber
EntrezGene
LocusSupplementaryData
-q31
@en
RefSeq
NM_001009552
@en
NM_002715
@en
UniProt
P62714
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P67775
@en
wikiPageUsesTemplate
subject
hypernym
comment
La protéine phosphatase 2 (PP2 ...... t comme suppresseur de tumeur.
@fr
Protein phosphatase 2 (PP2), a ...... may act as a tumor suppressor.
@en
Белок фосфатазы 2 (PP2) (англ. ...... каскадов, такие как , , и AKT.
@ru
プロテインホスファターゼ2 (protein phospha ...... のタンパク質が含まれ、PP2Aはがん抑制因子として機能する。
@ja
蛋白磷酸酶2（英語：Protein phosphatase ...... PP2A的底物都是信号传导级联反应中的癌蛋白，如AKT、和。
@zh
label
Protein phosphatase 2
@en
Protéine phosphatase 2
@fr
Фосфатаза 2
@ru
プロテインホスファターゼ2
@ja
蛋白磷酸酶2
@zh
sameAs
wasDerivedFrom
isPrimaryTopicOf
name
protein phosphatase 2, catalytic subunit, alpha isoform
@en
protein phosphatase 2, catalytic subunit, beta isoform
@en