RB-101
RB-101 is a drug that acts as an enkephalinase inhibitor, which is used in scientific research. RB-101 is a prodrug which acts by splitting at the disulfide bond once inside the brain, to form two selective enzyme inhibitors and blocking both types of the zinc-metallopeptidase enkephalinase enzymes. This inhibits the breakdown of the endogenous opioid peptides known as enkephalins. These two enzymes, aminopeptidase N (APN) and neutral endopeptidase 24.11 (NEP), are responsible for the breakdown of both kinds of enkephalin naturally found in the body, and so RB-101 causes a buildup of both Met-enkephalin and Leu-enkephalin.
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RB-101
RB-101 is a drug that acts as an enkephalinase inhibitor, which is used in scientific research. RB-101 is a prodrug which acts by splitting at the disulfide bond once inside the brain, to form two selective enzyme inhibitors and blocking both types of the zinc-metallopeptidase enkephalinase enzymes. This inhibits the breakdown of the endogenous opioid peptides known as enkephalins. These two enzymes, aminopeptidase N (APN) and neutral endopeptidase 24.11 (NEP), are responsible for the breakdown of both kinds of enkephalin naturally found in the body, and so RB-101 causes a buildup of both Met-enkephalin and Leu-enkephalin.
has abstract
RB-101 is a drug that acts as ...... linical trials are successful.
@en
CAS number
135949-60-9
PubChem
Wikipage page ID
16,636,681
page length (characters) of wiki page
Wikipage revision ID
1,021,801,900
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CAS number
ChemSpiderID
image
@en
IUPAC name
benzyl N--(L)-phenylalaninate
@en
PubChem
SMILES
CSCC[C@@H]N
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StdInChIKey
QXXMSEVVNUSHKJ-KEKPXRHTSA-N
@en
synonyms
RB-101; phenylmethyl -2-[amino]-3-phenylpropanoate
@en
verifiedrevid
448,079,539
wikiPageUsesTemplate
hypernym
comment
RB-101 is a drug that acts as ...... enkephalin and Leu-enkephalin.
@en
label
RB-101
@en